Can a common amino acid stop kidney stones from forming?
NCT ID NCT07465367
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether L-methionine, a natural amino acid, can make urine more acidic in people who form calcium phosphate kidney stones. These stones tend to form in alkaline urine, and current medications can sometimes make the problem worse. Fifteen participants will follow a special diet and take L-methionine, with urine samples collected to see if pH drops. It is a small, early-stage trial to see if this approach is worth further study.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
L-methionine (a dietary supplement)
What this could lead to
If it works, this could point toward a simple supplement to help prevent calcium phosphate kidney stones from coming back.
What could go wrong
This is a very small, early study with only 15 people. It may not show a clear effect, and results might not apply to everyone with kidney stones.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Study contacts
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Contact
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