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116076 trials found · Page 4922 of 5804
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Blood test may predict lung decline in rare disease
Knowledge-focused OngoingUp to 150 patients with hypersensitivity pneumonitis will be enrolled at 7 clinical centers across the United States. Patients will be followed for 24 months to determine if biomarkers in the blood can predict disease progression.
Sponsor: National Jewish Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Brain scans seek clues to mysterious bone pain
Knowledge-focused CompletedPain remains a common and frequently debilitating symptom, particularly during adulthood of Fibrous Dysplasia/McCune-Albright Syndrome (FD/MAS). For many FD/MAS patients, the amount of pain perceived is not commensurate with the level of detectable musculoskeletal pathology. Usin…
Phase: NA • Sponsor: Boston Children's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Tiny tube, big relief? new study tests scope treatment for pancreas pain
Symptom relief OngoingThis study is a prospective study designed to assess the effect of pancreatic endotherapy on quality of life, pain levels, pancreatic exocrine function, and endocrine function.
Sponsor: Ohio State University • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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Bee product gargle may soothe wisdom tooth pain
Symptom relief CompletedThe goal of this study is to examine the effects of propolis gargle on wound healing following third molar surgery and to compare it with chlorhexidine gluconate. The main question it aims to answer is: Is propolis-containing gargle safe and effective alternative to chlorhexidin…
Phase: NA • Sponsor: Ataturk University • Aim: Symptom relief
Last updated Jun 27, 2026 09:01 UTC
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Light therapy may cut braces time in half
Symptom relief CompletedThis study evaluated whether photobiomodulation (PBM), a form of low-level light therapy, can accelerate orthodontic tooth movement during canine distalization in adult patients undergoing fixed orthodontic treatment. Eighteen adult patients requiring extraction of maxillary fir…
Phase: NA • Sponsor: Wroclaw Medical University • Aim: Symptom relief
Last updated Jun 27, 2026 09:03 UTC
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Which breathing support works best for sick babies?
Knowledge-focused CompletedSevere acute viral bronchiolitis is the leading cause of pediatric intensive care admission. The first-line recommended ventilation support is continuous positive airway pressure (CPAP), which reduces the work of breathing (WOB) and improves gas exchange. Although Non invasive Po…
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Radiation after failed CAR t: tiny study halted early
Disease control TerminatedThis study is evaluating the safety and efficacy of using radiotherapy in participants who have refractory lymphoma shortly after receiving CAR T cell therapy (axicel or tisacel).
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Cancer Patients' sepsis mystery: do extra antibiotics help?
Knowledge-focused CompletedThis study evaluates the impact of aminoglycosides in hypotensive septic oncologic patients. In the oncologic patient population, sepsis is a major health concern due to high mortality rates and healthcare costs. Prior research shows aminoglycosides antibiotics are frequently use…
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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Hiprex trial for recurrent UTIs halted early – little data to go on
Disease control TerminatedThe purpose of this study is to measure the concentration of formaldehyde in the urine of women with recurrent urinary tract infections on Hiprex; and then, assuming its urinary presence is confirmed at the proper acid urinary pH, evaluate if such a therapy has favorable effects …
Phase: PHASE4 • Sponsor: University of Texas Southwestern Medical Center • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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Eye ultrasound may predict brain damage after cardiac arrest
Knowledge-focused OngoingIn sudden cardiac arrest patients with return of spontaneous circulation, brain damage is one of the main determinants of short-term mortality and poor prognosis (CPC 3-5). It is important to properly select group of patients in whom treatment is futile. According to current guid…
Sponsor: University Hospital Pilsen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Knee injury study reveals hidden stress in young athletes
Knowledge-focused OngoingThis study primarily aims to determine whether patients diagnosed with osteochondritis dissecans (OCD) of the knee experience psychological stress due to their diagnosis and treatment plan. Secondarily, this study aims to determine whether knee OCD patients experience a change in…
Sponsor: Boston Children's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Can a phone app help schizophrenia patients stay on track?
Knowledge-focused CompletedThe effective treatment of schizophrenia is very challenging due to a number of factors. These include issues such as poor engagement with treatment plans and care providers, limited contacts with providers due to under-resourced health services, and the challenges inherent to s…
Phase: NA • Sponsor: Centre for Addiction and Mental Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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Metabolic syndrome linked to persistent shoulder pain in new study
Knowledge-focused CompletedIn a longitudinal cohort project, the objective is to evaluate general prognostic and individual risk factors for long lasting shoulder pain, with a specific focus on evaluation of the association between metabolic syndrome and tendinopathy, while simultaneous adjusting for other…
Sponsor: Vejle Hospital • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:29 UTC
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Walking and thinking at the same time may reveal hidden MS balance issues
Knowledge-focused CompletedMultiple sclerosis (MS) is a chronic inflammatory autoimmune disease affecting the central nervous system. It is the leading cause of severe non-traumatic disability in young adults (20-40 years). It affects more than 540,000 individuals in Europe and around 2.8 million people wo…
Phase: NA • Sponsor: University Hospital, Limoges • Aim: Knowledge-focused
Last updated Jun 28, 2026 00:00 UTC
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Can a migraine drug stop Post-Concussion headaches?
Disease control CompletedThis is a United States Department of Defense funded Focused Program study that aims to identify mechanisms and predictors for persistent of post-traumatic headache attributed to mild traumatic brain injury, and identify methods of preventing post-traumatic headache persistence. …
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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EPO blood pressure mystery: small study halted early
Knowledge-focused TerminatedThe investigators hypothesize that compared to untreated controls, erythropoietin (EPO) therapy in anemic patients with chronic kidney disease will raise diastolic blood pressure (BP). The magnitude of increase in diastolic BP at 12 weeks after treatment will be related to two fa…
Phase: PHASE2 • Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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What makes muscles weak in frail seniors after a hip break?
Knowledge-focused CompletedAs people get older, the amount of skeletal muscle in the body can decrease. When the amount of this muscle in the body gets very low, there is an increased risk of falling, and not only is recovery to any injury slower, but more complications can be experienced following surgery…
Sponsor: University of Nottingham • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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Shock wave therapy fails to boost knee pain relief in small trial
Symptom relief CompletedPatellofemoral pain syndrome (PFPS) is a common cause of anterior knee pain and functional limitations in physically active individuals. Exercise-based rehabilitation is considered the primary treatment approach, yet a proportion of patients experience persistent symptoms. Extrac…
Phase: NA • Sponsor: Uğur Can Yalaki • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Brain scans reveal how retinal disease rewires neural networks
Knowledge-focused Recruiting nowThe Rothschild Foundation A Hospital follows a cohort of approximately 300 patients with hereditary retinal dystrophy. These patients are followed in ophthalmology consultation every year. In order to plan the MRI on the day of the annual consultation and to avoid additional trav…
Sponsor: Fondation Ophtalmologique Adolphe de Rothschild • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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New registry aims to unravel mysteries of long COVID
Knowledge-focused Recruiting nowThe goal of this observational study is to deepen our understanding of long COVID by determining the prevalence of the main complications and medium- to long-term sequelae of COVID-19 in Navarre. Sociodemographic variables such as age, sex, ethnicity, smoking history, and comorb…
Sponsor: Fundacion Miguel Servet • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC