Knee cartilage repair: can ACI surgery get you moving again?

NCT ID NCT06921889

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows 47 adults who are scheduled for autologous chondrocyte implantation (ACI) to repair knee cartilage injuries. Researchers will measure knee movement, balance, and walking ability before surgery and again 6 months after. The goal is to understand how knee function changes after ACI and help set realistic expectations for recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Autologous Chondrocyte Implantation (ACI) - a procedure using the patient's own cartilage cells to repair knee cartilage damage.

What this could lead to

If successful, this study could help doctors and patients know what to expect after ACI surgery and identify common problems that physiotherapy might fix.

What could go wrong

This is a small, observational study (47 people) that only follows patients for 6 months. It does not test a new treatment or prove long-term benefits.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chondromalacia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Addenbrooke's Hospital

    NOT_YET_RECRUITING

    Cambridge, CB2 0QQ, United Kingdom

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  • Chapel Allerton Orthopaedic Centre

    RECRUITING

    Leeds, LS7 4SA, United Kingdom

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  • New Cross Hospital

    RECRUITING

    Wolverhampton, WV10 0QP, United Kingdom

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  • Royal National Orthopaedic Hospital

    RECRUITING

    Stanmore, HA7 4LP, United Kingdom

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  • Royal Orthopaedic Hospital

    NOT_YET_RECRUITING

    Birmingham, B31 2AP, United Kingdom

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  • Southampton General Hospital

    NOT_YET_RECRUITING

    Southampton, SO16 6YD, United Kingdom

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  • Trafford General Hospital

    RECRUITING

    Manchester, M415SL, United Kingdom

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