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127005 trials found · Page 4917 of 6351
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Stomach cancer surgery study maps hidden spread
Knowledge-focused Recruiting nowThis study aims to evaluate lymph node metastasis and tumor deposit in the posterior gastric mesentery following distal gastrectomy with D2 lymphadenectomy plus complete mesogastric excision (CME) in gastric cancer.
Sponsor: Jichao Qin • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:38 UTC
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No-Opioid anesthesia may improve recovery after gallbladder surgery
Symptom relief CompletedThe aim of this study is to compare the quality of recovery from general anesthesia and surgery using the quality of recovery 15 item scale (QoR-15) for participant's receiving opioid-Sparing anesthesia with those receiving standard opioid-containing anesthesia in Patients underg…
Sponsor: Ain Shams University • Aim: Symptom relief
Last updated Jun 27, 2026 07:52 UTC
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Do 'Do not Resuscitate' orders raise death risk in ICUs? new study investigates
Knowledge-focused OngoingThe hypothesis of the study is that a resuscitation order other than full code is associated with increased mortality among critically ill patients. By incorporating conventional variables associated with death such as age, sex, and Simplified Acute Physiological Score, as well a…
Sponsor: Karolinska Institutet • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:21 UTC
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New program aims to ease cancer Patients' scan anxiety
Symptom relief Recruiting nowThis is a behavioral trial study to pilot test a stress management intervention for people with cancer who are undergoing routine cancer scans. The study will involve two pilot testing phases. Initial feasibility will be determined in an Open Trial phase, to inform any needed rev…
Sponsor: Hackensack Meridian Health • Aim: Symptom relief
Last updated Aug 06, 2026 00:00 UTC
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Vitamin B1 shows promise for Kids' hearts after hole closure
Disease control CompletedCurrently, research on the effect of thiamine administration during transcatheter closure on the structure and function of the left ventricle by examining levels of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in children with left to right shunt congeni…
Early phase 1 • Sponsor: Universitas Sumatera Utara • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Blood-Derived filler could replace donor bone in dental implants
Disease control CompletedTwenty-eight patients seeking prosthetic replacement of non-restorable single rooted maxillary teeth by dental implant will be selected from the outpatient Clinic of Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Mansoura University
Sponsor: Mansoura University • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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Digital rehab vs. paper brochure: which works better for slipped discs?
Symptom relief CompletedThe aim of this study was to develop an asynchronous, web-based telerehabilitation exercise and monitoring program and to compare its effectiveness with a traditional brochure-based home exercise program in patients with lumbar disc herniation. The study was designed as a randomi…
Sponsor: Necmettin Erbakan University • Aim: Symptom relief
Last updated Jun 27, 2026 12:01 UTC
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Scientists probe why belly fat ignores insulin
Knowledge-focused Recruiting nowAdults who gain most of their excess weight in the abdominal area typically do not respond to insulin in the same way as lean adults. Researchers are trying to understand why fat tissue responds differently in people with different body types.
Early phase 1 • Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Zirconia vs titanium: which dental implant heals bone better?
Knowledge-focused CompletedDental implants have been on the market for several years and they are routinely used to replace single/multiple missing teeth with a high success rate. However, there is still a limited number of studies comparing hydrophilic titanium and zirconia implants. In addition, there is…
Sponsor: Queen Mary University of London • Aim: Knowledge-focused
Last updated Jul 19, 2026 00:00 UTC
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ICU intubation showdown: hyperangulated vs. macintosh blades
Knowledge-focused Recruiting nowTracheal intubation in the intensive care unit (ICU) is associated with high incidence of difficult intubation and complications. Videolaryngoscopes (VLs) devices have been proposed to improve airway management, and the use of VLs are recommended as first-line or after a first-at…
Sponsor: Hospital Clinico Universitario de Santiago • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:12 UTC
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Mediterranean diet shows promise for metabolic health in psychiatric patients
Disease control CompletedBackground: Dietary modifications, like changing macronutrient distribution and improving food quality, are the main therapeutic approaches for managing oxidative stress, inflammation, and metabolic syndrome. Mediterranean diet is scientifically endorsed as promoting healthy agin…
Sponsor: King Saud University • Aim: Disease control
Last updated Jun 26, 2026 15:01 UTC
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Workplace nap pods boost Well-Being, study finds
Symptom relief CompletedThis study examines whether access to a rest cabin in the workplace supports employee well-being. Employees of a Canadian insurance company are randomly assigned to one of two groups: immediate access to the rest cabin or a waiting-list control group that receives access after on…
Sponsor: Laval University • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC
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Can a flicker of movement reveal hidden awareness?
Knowledge-focused Recruiting nowThe goal of this observational study is to learn about the micro-movements in patients with prolonged disorders of consciousness. The main questions it aims to answer are: Use the neuropsychological paradigm model to monitor micro-movements, assess the patient's remaining level …
Sponsor: First Affiliated Hospital of Zhejiang University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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Sitting less, living better: new study targets diabetes in black seniors
Knowledge-focused CompletedThe disparate burden of Type 2 Diabetes (T2D) faced by Black individuals makes attention to preventing or delaying the development of T2D and its associated cardiovascular (CV) complications, essential. Similar to differences in cardiovascular disease (CVD) rates across racial a…
Phase 2 • Sponsor: University of Minnesota • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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New sensor could replace Finger-Stick ketone tests for diabetes patients
Diagnosis CompletedThe goal of this 14-day randomized pilot trial is to assess the accuracy of a continuous ketone monitoring (CKM) system when compared to standard point-of-care capillary ketone monitors in individuals with type 1 diabetes on insulin pump therapy. The main question it aims to answ…
Sponsor: McGill University • Aim: Diagnosis
Last updated Jun 27, 2026 07:51 UTC
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Apple watch could predict brain tumor complications
Knowledge-focused PausedThe purpose of this research is to learn more about how what the Apple watch measures, in terms of walking data, heart rate, breathing rate, and sleep habits, relates to how participants feel. During the course of the treatment, the symptoms participants experience change, and wh…
Sponsor: Case Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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New COPD drug shows promise in Real-World romanian study
Symptom relief CompletedThe purpose of this study is to describe patients' clinical and self-reported outcomes of treatment with budesonide / glycopyrronium / formoterol Metered dose inhaler (BGF MDI) in Romania in real-life setting, up to 6 month of observation period. The study will focus primarily on…
Sponsor: AstraZeneca • Aim: Symptom relief
Last updated Jun 27, 2026 08:06 UTC
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Sweet vs. cool: do men and women react differently to E-Cig flavors?
Knowledge-focused CompletedThe primary objective is to examine the influence of sex on sensory effects, appeal, and reinforcing value of nicotine containing e-cigs in popular flavor components; sweet and cooling.
Sponsor: Yale University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Heart failure drug trial pulled before it even started
Disease control CancelledThis is a Phase 2, multicenter, randomized, double-blind, placebo-controlled study including approximately 130 randomized HF patients with heart failure with mildly reduced or preserved ejection fraction (LVEF ≥45%), to assess efficacy and safety of CDR132L on reverse remodeling.…
Phase 2 • Sponsor: Cardior Pharmaceuticals GmbH • Aim: Disease control
Last updated Jul 09, 2026 00:00 UTC
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Mountain-Air breathing trick may boost MS muscle strength
Knowledge-focused Recruiting nowThis study aims to understand the mechanisms of a novel intervention involving breathing short durations of low levels of oxygen for persons with multiple sclerosis (MS). This intervention with low levels of oxygen is called Acute Intermittent Hypoxia (AIH), the levels of oxygen …
Sponsor: Shirley Ryan AbilityLab • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC