Can a flicker of movement reveal hidden awareness?
NCT ID NCT06406413
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at very small movements (micro-movements) in patients who have been unconscious for over a month after a severe brain injury. Researchers will use emotional stimuli to see if these movements, along with brain scans, can detect hidden awareness. The goal is to better classify each patient's level of consciousness and improve predictions of recovery. 179 participants will be followed for 6 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to better ways to detect awareness in patients who appear unresponsive, improving diagnosis and care.
- What could go wrong
- This is an observational study, not a treatment trial. It may not directly change patient outcomes, and results may not apply to all patients.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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First Affiliated Hospital,Zhejiang University
RECRUITINGHanzhou, Zhejiang, 310003, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Sound waves to wake the brain? new study tests ultrasound for consciousness disorders
- Could sound waves wake the brain? new trial tests ultrasound for severe injury