Can a smile reveal hidden consciousness? new study investigates
NCT ID NCT06088628
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at micro-expressions—tiny, involuntary facial movements—in 200 patients with prolonged disorders of consciousness. Researchers will use emotional stimuli to trigger these expressions and combine them with EEG and MRI scans. The goal is to better classify levels of consciousness and explore remaining brain function.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could improve how doctors diagnose levels of consciousness in patients with severe brain injuries.
- What could go wrong
- This is an early observational study, so it may not lead to immediate clinical changes. Results may not apply to all patients.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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First Affiliated Hospital,Zhejiang University
RECRUITINGHangzhou, Zhejiang, 310003, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a flicker of movement reveal hidden awareness?
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