Blood-Derived filler could replace donor bone in dental implants
NCT ID NCT07445776
First seen Mar 31, 2026 · Last updated Jun 22, 2026 · Updated 13 times
Summary
This study tested two materials for filling the gap around a dental implant placed right after tooth removal: e-PRF (made from the patient's own blood) and allograft (donor bone). Twenty-eight patients with damaged front teeth received one of the two fillers. The main goal was to see how stable the implant became and how much bone was lost around it. The results could help dentists choose a simpler, natural option for implant success.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Faculty of Dentistry, Mansoura University
Al Mansurah, 002, Egypt
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
e-PRF (extended platelet-rich fibrin) and allograft (donor bone material)
What this could lead to
If e-PRF works as well as allograft, it could offer a simpler, cheaper option for filling gaps around dental implants using the patient's own blood products.
What could go wrong
This is a small, completed study with only 28 patients, so results may not apply to everyone. e-PRF is still experimental for this use and may not be as effective as standard allograft.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.