Blood-Derived filler could replace donor bone in dental implants

NCT ID NCT07445776

Completed Disease control Sponsor: Mansoura University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested two materials for filling the gap around a dental implant placed right after tooth removal: e-PRF (made from the patient's own blood) and allograft (donor bone). Twenty-eight patients with damaged front teeth received one of the two fillers. The main goal was to see how stable the implant became and how much bone was lost around it. The results could help dentists choose a simpler, natural option for implant success.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: e-PRF (extended platelet-rich fibrin) and allograft (donor bone material)
What this could lead to: If e-PRF works as well as allograft, it could offer a simpler, cheaper option for filling gaps around dental implants using the patient's own blood products.
What could go wrong: This is a small, completed study with only 28 patients, so results may not apply to everyone. e-PRF is still experimental for this use and may not be as effective as standard allograft.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GAP FILLING WITH ALLOGRAFT GAP FILLING WITH E-PRF IMMEDIATE IMPLANT PLACEMENT

Contacts and locations

Locations

Faculty of Dentistry, Mansoura University

Al Mansurah, 002, Egypt

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