Mountain-Air breathing trick may boost MS muscle strength

NCT ID NCT06276634

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether breathing short bursts of low-oxygen air (like at high altitude) can improve ankle strength and brain activity in people with multiple sclerosis. Twenty-one adults with relapsing forms of MS will undergo 15 cycles of low oxygen followed by normal air in one session. Researchers will measure muscle strength and use brain scans to understand how the intervention works.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Acute Intermittent Hypoxia (AIH) - brief breathing of low oxygen air

What this could lead to

If it works, this could point toward a new way to improve strength in people with MS without drugs.

What could go wrong

This is a very small early study (21 people) looking at brain changes, not a proven treatment. The low-oxygen breathing may not lead to lasting strength gains.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic progressive multiple sclerosis Hypoxia multiple sclerosis relapsing-remitting multiple sclerosis secondary progressive multiple sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Shirley Ryan AbilityLab

    RECRUITING

    Chicago, Illinois, 60611, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact