Mountain-Air breathing trick may boost MS muscle strength

NCT ID NCT06276634

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether breathing short bursts of low-oxygen air (like at high altitude) can improve ankle strength and brain activity in people with multiple sclerosis. Twenty-one adults with relapsing forms of MS will undergo 15 cycles of low oxygen followed by normal air in one session. Researchers will measure muscle strength and use brain scans to understand how the intervention works.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Acute Intermittent Hypoxia (AIH) - brief breathing of low oxygen air
What this could lead to
If it works, this could point toward a new way to improve strength in people with MS without drugs.
What could go wrong
This is a very small early study (21 people) looking at brain changes, not a proven treatment. The low-oxygen breathing may not lead to lasting strength gains.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MULTIPLE SCLEROSIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Shirley Ryan AbilityLab

    RECRUITING

    Chicago, Illinois, 60611, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.