Can a gentle electric zap to the brain restore memory in MS?

NCT ID NCT05958381

First seen Aug 14, 2026 ยท Last updated Aug 14, 2026

Summary

This trial tests whether a mild electric current applied to a brain area linked to memory can improve verbal recall in people with relapsing-remitting multiple sclerosis. Participants will receive either active or sham stimulation during cognitive tasks, and their performance will be measured before, shortly after, and two months later. The study also looks at how individual differences, such as baseline cognition and concussion history, might influence treatment response.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
High-definition transcranial direct current stimulation (tDCS) delivered via a Neuroelectrics Starstim device
What this could lead to
If effective, this could offer a non-invasive, drug-free way to ease memory and thinking problems in people with multiple sclerosis.
What could go wrong
This is an early-stage trial, and results may not be conclusive or widely applicable. The stimulation is low-level, but individual responses can vary, and benefits may not last.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The University of Texas at Dallas

    RECRUITING

    Richardson, Texas, 75080, United States

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