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127005 trials found · Page 4824 of 6351
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Diabetes drug empagliflozin studied for kidney disease mineral effects
Knowledge-focused Recruiting nowThis study aims to better understand electrolyte handling in patients with autosomal dominant polycystic kidney disease treated with the SGLT2 inhibitor Empagliflozin. Patients will be randomized into two groups and take Empagliflozin or a Placebo for 2 weeks with a wash-out per…
Phase 2 • Sponsor: Cantonal Hospital Graubuenden • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:19 UTC
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Ultrasound-Guided needle therapy may ease menstrual cramps
Symptom relief Recruiting nowthe study is to evaluated dopplar guided angiopuncture efficacy and safety in patients with dysmenorrhea
Sponsor: City University of Hong Kong • Aim: Symptom relief
Last updated Jun 26, 2026 17:52 UTC
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Simple breath test could revolutionize asthma checkups
Knowledge-focused Recruiting nowThe goal of this longitudinal observational study is to learn if impulse oscillometry (IOS) has an added value in asthma monitoring in adult asthma patients who are prescribed a change in asthma maintenance therapy. The main questions it aims to answer are: * Is there a differen…
Sponsor: Universitair Ziekenhuis Brussel • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:06 UTC
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Could your meds make you fall? massive study investigates
Knowledge-focused OngoingPurpose: This study aims to validate the medication entries in the PRISCUS list-a German expert-based compilation of potentially inappropriate medications for older adults-and to identify additional medications that may pose a fall risk but are not yet included. Study Design: …
Sponsor: Charite University, Berlin, Germany • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:52 UTC
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New ultrasonic tool may ease pain and swelling after wisdom tooth removal
Symptom relief CompletedIn the surgical removal of impacted mandibular third molars, ultrasonic surgical devices (piezosurgery) have been introduced with the expectation of reducing postoperative complications such as swelling, pain, and trismus, compared with conventional rotary instruments. To objecti…
Sponsor: Le Huynh Thien An • Aim: Symptom relief
Last updated Jun 27, 2026 07:52 UTC
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Grip strength may predict cancer patient survival
Knowledge-focused CompletedThis prospective observational cohort study aims to evaluate whether integrated bedside assessment of handgrip strength, cachexia-related indices, body composition, and patient-reported outcomes improves short-term prognostic stratification in hospitalized patients with metastati…
Sponsor: Ankara Etlik City Hospital • Aim: Knowledge-focused
Last updated Jul 03, 2026 00:00 UTC
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Heart failure patients and caregivers get a boost from Nurse-Led training
Symptom relief Recruiting nowThe current study intends to examine the influence of nurse-led education on patients with chronic heart failure and their caregivers, with the goal of optimizing care for both and improving patients\' clinical outcomes.
Sponsor: Hellenic Mediterranean University • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Spine surgery clues: could your bones predict recovery?
Knowledge-focused Recruiting nowThe present study is related to the project "ORTHOSPINE FITNESS: WHICH MARKERS OF MUSCULOSKELETAL HEALTH CAN EXPLAIN COMPLICATIONS IN SPINE SURGERY?", winner of the Ministry of Health Call, financed by the European Union, "M6/C2\_CALL 2023", Project Code " PNRR- MCNT2-2023-123780…
Sponsor: Istituto Ortopedico Rizzoli • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Natural blend may soothe hemorrhoid pain, study finds
Symptom relief CompletedTo demonstrate the clinical efficacy of the combination of Aesculus hippocastanum, Polygonum acre, Smilax Pepyracea, and rutin in tablets in improving local symptoms (bleeding, pain, thrombosis, perianal dermatitis, hemorrhoidal nipple prolapse) assessed using a 100mm visual scal…
Phase 4 • Sponsor: Fundação Educacional Serra dos Órgãos • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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Mushroom extract may fight smoke damage, early trial hints
Disease control CompletedThe goal of this randomized controlled clinical trial is to evaluate whether polysaccharide peptide (PsP) supplementation from Ganoderma lucidum can modulate biomarkers of oxidative stress, inflammation, nicotine exposure, and stress response in adults exposed to cigarette smoke.…
Sponsor: University of Brawijaya • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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Breathe through the pain: student midwives test simple technique for easier labor
Symptom relief CompletedThis randomized controlled trial aimed to evaluate the effect of breathing exercises applied under the guidance of student midwives during labor on labor pain, labor duration, and birth satisfaction. The intervention group received structured breathing exercises guided by student…
Sponsor: Antalya Bilim University • Aim: Symptom relief
Last updated Jun 27, 2026 09:02 UTC
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Which anesthesia is best for a common gynecological procedure? new study investigates
Symptom relief CompletedBackground: Diagnostic hysteroscopy is a common ambulatory gynecological procedure that may be associated with perioperative discomfort and postoperative pain. The optimal anesthetic technique for improving patient comfort while ensuring rapid recovery remains controversial. This…
Sponsor: Hopital Charles Nicolle • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Can an app keep seniors moving? new study puts digital coaching to the test
Prevention CompletedThe objective of WP2 of the Active3 project is to develop a digital solution for promoting and monitoring physical activity in social settings (real or virtual) that implements a Preventive Medicine approach to healthy aging. Specifically, the objective of the action related to …
Sponsor: Politecnico di Milano • Aim: Prevention
Last updated Jun 27, 2026 08:12 UTC
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New device aims to reduce dangerous oxygen drops in preterm infants
Disease control Recruiting nowThe goal of this clinical trial is to learn if the use of PIMUN(medical device) works to reduce the intermittent hypoxemia of 24-34 weeks of birth gestational age babies. . It will also learn about the safety of the use of PIMUN. The main questions it aims to answer are: Does PI…
Sponsor: Pontificia Universidad Catolica de Chile • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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Gel boosts gum surgery results in small trial
Disease control CompletedThe study aimed to evaluate the effect of Hyaluronic Acid-based gel use in addition to the coronally advanced flap (CAF) technique in type 1 gingival recession (RT1) on postoperative morbidity, clinical parameters, and patient satisfaction, analyzed at baseline and 6 months.
Phase 1/2 • Sponsor: Ordu University • Aim: Disease control
Last updated Jun 27, 2026 09:08 UTC
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New study tracks kidney health in myeloma patients on daratumumab
Knowledge-focused CompletedThe goal of this prospective observational study is to understand changes in urinary and blood biomarkers associated with acute kidney injury (AKI) in patients newly diagnosed with multiple myeloma and being treated with Daratumumab SC. The aims of the study are: To measure chan…
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Can fun outings beat the blues? new study tests community activities for depression
Symptom relief By invitation onlyThis project tests whether a health outreach intervention that promotes engagement in rewarding, community-based recreational and social activities can produce greater improvements in depressive symptoms, adiposity, and physical activity among people from underresourced communiti…
Sponsor: Rush University Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC
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Teacher training may boost ADHD support in classrooms
Knowledge-focused OngoingThis interventional study aims to evaluate the effectiveness of a structured teaching program designed to improve primary school teachers' knowledge and classroom performance regarding the management of children diagnosed with Attention-Deficit/Hyperactivity Disorder (ADHD). The …
Sponsor: Dlniya Ismail Rashid • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Can a Pharmacist's guidance with a glucose monitor improve diabetes control?
Disease control OngoingThis is a pilot study. The goal of this prospective cohort study is to determine impact of pharmacist-led continuous glucose monitoring on glycemic control and health behavior change in people with type 2 diabetes. The main questions it aims to answer are: 1. to assess change in…
Sponsor: University of South Florida • Aim: Disease control
Last updated Aug 12, 2026 00:00 UTC
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New breathing method may speed recovery after heart bypass
Symptom relief Recruiting nowIntroduction: The thoracoabdominal rebalancing (TAR) method aims to promote diaphragmatic juxtaposition, in addition to seeking to increase respiratory muscle strength and adjust muscle tone. However, scientific publications on this method in heart patients undergoing coronary ar…
Sponsor: Instituto de Cardiologia do Rio Grande do Sul • Aim: Symptom relief
Last updated Jun 27, 2026 12:24 UTC