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116076 trials found · Page 4449 of 5804
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Breathe away the pain: new combo therapy for sore shoulders
Symptom relief CompletedRotator cuff impingement syndrome is one of the most common causes of shoulder pain and functional limitation, with manual therapy frequently employed in its management. This study aimed to investigate the additional effects of incorporating breathing exercises into manual therap…
Phase: NA • Sponsor: Istanbul Medipol University Hospital • Aim: Symptom relief
Last updated Jun 26, 2026 18:38 UTC
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Which workout wins for diabetes? circuit vs. strength training showdown
Disease control CompletedPatients with type II diabetes are at high risk of developing cardiovascular diseases due to increased blood sugar, inflammation, insulin resistance, and physical inactivity. The effectiveness of exercises in improving cardiopulmonary fitness have not been well documented and pra…
Phase: NA • Sponsor: Riphah International University • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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Home prehab: could exercise and diet before pancreatic cancer surgery improve recovery?
Symptom relief Recruiting nowThe purpose of the study is to examine the feasibility and acceptability of an exercise and nutrition "prehabilitation" program for patients preparing for pancreatic cancer resection (removal).
Phase: NA • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Can a parent program boost Kids' mental health and activity? study says maybe.
Knowledge-focused CompletedThis study evaluates feasibility and preliminary efficacy of a parent-based prevention program to promote social-emotional and lifestyle behavior health among 3- to 9-year-old children in families experiencing major stressors.
Phase: NA • Sponsor: University of South Carolina • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:01 UTC
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Blood test may predict dangerous side effects of cancer immunotherapy
Knowledge-focused Recruiting nowThe goal of this observational study is to explore the value of blood biomarkers for the purpose of predicting irAE development in cancer patients treated with immune checkpoint inihibitors (ICI) alone or in combination with other treatments (chemotherapy, radiotherapy and target…
Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated Jun 28, 2026 00:00 UTC
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One-Minute chair test could revolutionize blood clot recovery prediction
Knowledge-focused Recruiting nowThe objective of the study is to evaluate the prognostic performance of the chair lift test in the initial assessment of the severity of non-severe pulmonary embolism in hospitalized patients, in comparison with the current pulmonary embolism risk stratification score using the s…
Phase: NA • Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Peer ambassadors may boost clinical trial enrollment in gynecologic cancer
Knowledge-focused CompletedThe overall objective of this study is to design and evaluate a peer ambassador intervention to improve gynecologic cancer trial enrollment. The primary Aim is to determine the possibility of using peer ambassadors to increase discussion, awareness, and enrollment of patients wit…
Phase: NA • Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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Tailored therapy shows promise for teens with headaches
Symptom relief CompletedThis project was an empirical single-case experimental design (SCED) study conducted as part of a DClinPsy doctoral thesis completed by one of the researchers. The study used a brief and highly personalised psychological intervention for adolescents experiencing headaches. The ai…
Phase: NA • Sponsor: Royal Holloway University • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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Meditation might sharpen your mind, new study hints
Knowledge-focused Recruiting nowThis is a prospective cohort study with 52 meditators and 52 controls. These groups will be contacted at a singular timepoint, during which they will take surveys and cognitive tests, which will be used to assess cognitive and emotional outcomes. The meditator group will be recru…
Sponsor: Balachundhar Subramaniam • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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New dental membrane monitored for better healing after surgery
Knowledge-focused OngoingThe goal of this observational study is to measure in real practice the performance and safety of RTR+Membrane, a synthetic dental membrane for guided tissue regeneration in periodontal or dental implant surgery. The main question it aims to answer is to measure the post-operativ…
Sponsor: Septodont • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Low FODMAP diet eases gut troubles in SIBO patients
Symptom relief CompletedThis study aims to assess the impact of a low FODMAP diet (LFD) on gastrointestinal symptoms and nutritional status in individuals diagnosed with small intestinal bacterial overgrowth (SIBO). Participants were randomly assigned to either an intervention group or a control group f…
Phase: NA • Sponsor: Warsaw University of Life Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 09:07 UTC
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ICU alarm overload: new protocol aims to cut noise and save lives
Knowledge-focused Recruiting nowResuscitation patients are monitored for various physiological parameters. When these parameters exceed abnormal thresholds, an audible alarm is triggered. Given the complexity of physiological situations and the number of monitored parameters, the number of alarms within an inte…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Saint Etienne • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Pfizer's new cancer combo shows early promise but trial halted
Disease control TerminatedThis study aims to evaluate the safety, and early signals of anti-tumor activity of PF-07820435 when administered alone (Part 1A) or in combination with sasanlimab (Part 1B; Part 2) in patients with selected advanced or metastatic solid tumors. Part 1 will be dose-finding and Par…
Phase: PHASE1 • Sponsor: Pfizer • Aim: Disease control
Last updated Jun 26, 2026 18:06 UTC
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Surgeons test High-Tech goggles for better shoulder replacements
Knowledge-focused CompletedA pilot Single-Arm, Multicenter, Prospective, Post-Market 6 months Follow-Up Clinical Investigation to Evaluate the Safety and Effectiveness of the Blueprint Mixed Reality HOLOBLUEPRINT™ (HOLOBLUEPRINT™).
Sponsor: Stryker Trauma and Extremities • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:37 UTC
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Tooth infection showdown: which filling material heals better?
Disease control CompletedThe aim of this study is to compare two biomaterials used for retrograde obturation during apical surgery. This surgery is indicated in healthy patients when root canal treatment (endodontics) has failed to eliminate a periapical lesion (a persistent infection in the root of the …
Phase: NA • Sponsor: University of Valencia • Aim: Disease control
Last updated Jul 15, 2026 00:00 UTC
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Scientists zap brains to map fear circuits
Knowledge-focused OngoingThe purpose of this study is to examine which event-related potentials (ERPs) and event-related oscillations (EROs) are associated with fear conditioning, avoidance learning, and memory recall for fear and avoidance, where are the source generators of the observed scalp EEG activ…
Phase: NA • Sponsor: The University of Texas Health Science Center, Houston • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Ventilator study aims to personalize breathing support for ARDS patients
Knowledge-focused Recruiting nowThis study aim to compare the effect of Positive End Expiratory Pressure (PEEP) on ventilation/perfusion mismatch in two phenotypes of patients with moderate-to-severe Acute Respiratory Distress Syndrome (ARDS), characterized by their respiratory system elastance (Ers). Ventilati…
Phase: NA • Sponsor: University Hospital, Angers • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Can ultrasound help doctors give the right amount of fluids in septic shock?
Knowledge-focused CompletedFluid management is one of the key issues in the initial management of septic shock (SS). Fluid overload and hypovolemia have been associated with increased mortality in several trials. Transthoracic echocardiography (TTE) and lung ultrasound are recommended for haemodynamic asse…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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New ultrasound tech could reveal hidden blood flow in overused tendons
Knowledge-focused Recruiting nowThe goal of this observational study is to test whether a new ultrasound method, called SUper Resolution ultrasound imaging of Erythrocytes (SURE), can image the small blood vessels found in tendons of persons with a tendon overuse injury (tendinopathy). The main questions it aim…
Sponsor: University Hospital Bispebjerg and Frederiksberg • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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New tool aims to detect brain fog in cancer patients early
Knowledge-focused Recruiting nowThis clinical trial evaluates the use of a tool kit, Stress, Affect, Language and Speech Analysis (SALSA), for early identification of cognitive side effects of immunotherapy compared to the standard of care assessment.
Sponsor: Masonic Cancer Center, University of Minnesota • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC