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116076 trials found · Page 4390 of 5804
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Small study hopes to find which heart surgery is easier on the body
Knowledge-focused OngoingThe goal of this observational study is to evaluate pulmonary function, respiratory muscle strength, peripheral muscle strength, and functional capacity in adult patients undergoing either minimally invasive cardiac surgery (via mini-thoracotomy) or conventional sternotomy for co…
Sponsor: Zehra Can Karahan • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:07 UTC
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New wearable could spot opioid breathing danger
Knowledge-focused CompletedAn observational study will be conducted in approximately 14 participants to evaluate the ability of a wearable, wireless acoustic Respiratory Monitoring System (RMS) to accurately measure a participant's respiratory rate, tidal volume, minute ventilation, and duration of apnea i…
Sponsor: Jeffrey Joseph • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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Game on: mobile app helps kids with kidney disease take control
Disease control CompletedThe aim of this study was to investigate the effect of a mobile game application developed for children with Chronic Renal Failure (CRF) on disease management. The study was a randomized controlled trial. The study sample consisted of 68 children diagnosed with CRF, including th…
Phase: NA • Sponsor: Akdeniz University • Aim: Disease control
Last updated Jun 26, 2026 15:16 UTC
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One shot before back surgery may cut painkiller need
Symptom relief Recruiting nowResearchers are considering Dexamethasone as preemptive medication before minimally invasive spine fusion surgery to minimize postoperative back pain with minimal side effects, aiming to enhance the effectiveness of surgery and improve patient outcomes.
Phase: PHASE4 • Sponsor: Potsawat Surabotsopon • Aim: Symptom relief
Last updated Jun 26, 2026 15:16 UTC
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New study maps hidden cancer spread in stomach surgery
Knowledge-focused Recruiting nowThis study aims to evaluate the tumor deposit at the fusion site of the right gastric mesentery and left gastric mesentery in the patients with gastric cancer who received proximal gastrectomy.
Sponsor: Jichao Qin • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:12 UTC
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Faster braces, less bone loss? new study tests PRP and decortication
Knowledge-focused CompletedAlveolar bone loss and fenestration are the most prevalent bone defects that often result in root exposure, gingival recession, and potential treatment relapse or failure. These issues present complications in orthodontic therapy. Hence, reducing the length of orthodontic therapy…
Phase: NA • Sponsor: Tanta University • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:23 UTC
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Zapping muscles in the ICU: a simple way to stop weakness?
Disease control CompletedTo prevent the development of ICUAW, both early mobilization and neuromuscular electrical stimulation (NMES) have been shown to prevent muscle atrophy in critically ill patients by preserving muscle mass. Furthermore, it is of great value that muscle assessment using kinesiologic…
Phase: NA • Sponsor: Universidade Federal do Rio de Janeiro • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Hidden diabetes worsens ICU outcomes, study finds
Knowledge-focused CompletedIn the Netherlands, patients admitted to the ICU are classified as having diabetes based on whether their medical records indicate glucose management medication use (Dutch National Intensive Care Evaluation (NICE) Registry). However, this approach does not identify patients with …
Sponsor: University Medical Center Groningen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Heart monitoring breakthrough: 14 days vs. 24 hours for MVP patients
Knowledge-focused CompletedMitral valve prolapse (MVP) affects up to 3% of the general population and a small subset of patients is at risk for ventricular arrhythmias. This subgroup is referred to as AMVP (arrhythmic MVP) and was recently defined using the following criteria: (1) Presence of MVP), (2) Ven…
Phase: NA • Sponsor: Universitaire Ziekenhuizen KU Leuven • Aim: Knowledge-focused
Last updated Jul 23, 2026 00:00 UTC
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Can colored light masks soothe dry, irritated eyes?
Symptom relief Recruiting nowThe use of photobiomodulation or low-level light therapy (LLLT) in the ophthalmic field stemmed from dermatology which has shown impact on skin blood flow and regeneration. There has been a rise in clinical interest with emerging evidence in the benefits of photobiomodulation in …
Phase: NA • Sponsor: Aston University • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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Smart insoles could reveal hidden clues in rare childhood diseases
Knowledge-focused Recruiting nowThe purpose of this research is (1) to identify disease specific walking-related digital biomarkers of disease severity, and (2) monitor longitudinal changes in natural environments, for extended periods of time, in DMD and SMA.
Sponsor: Columbia University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Simple shoulder exercises speed recovery after rotator cuff surgery
Symptom relief CompletedThe study investigates the effect of accelerate rehabilitation protocol(adding scapular strengthen exercises (lower trapezius and serratus anterior) from week 1) after arthroscopic rotator cuff repair on scapular upward rotation during shoulder elevation.
Phase: NA • Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 27, 2026 11:03 UTC
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Ice on trigger points calms Swimmers' tremors, small study hints
Symptom relief CompletedThis study examines whether local cryostimulation of myofascial trigger points can reduce physiological tremor that occurs after intense physical exercise. Thirty-four adolescent competitive swimmers participate in a randomized crossover study comparing two conditions: local ice …
Phase: NA • Sponsor: Józef Piłsudski University of Physical Education • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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Brain waves may reveal pain before you wake up
Knowledge-focused CompletedThe goal of this study is to explore whether specific intraoperative EEG signals (brain waves or neuronal electrical activity) are associated with the severity of acute postoperative pain.
Sponsor: University of Chile • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Digital rehab vs. paper brochure: which works better for slipped discs?
Symptom relief CompletedThe aim of this study was to develop an asynchronous, web-based telerehabilitation exercise and monitoring program and to compare its effectiveness with a traditional brochure-based home exercise program in patients with lumbar disc herniation. The study was designed as a randomi…
Phase: NA • Sponsor: Necmettin Erbakan University • Aim: Symptom relief
Last updated Jun 27, 2026 12:01 UTC
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New oxygen mask could help heart patients breathe easier after surgery
Symptom relief OngoingHigh-flow oxygen therapy has been applied after extubation in cardiac surgery patients with a well-known successful efficacy. The current authors plan to conduct a prospective, randomized, controlled study of the Asymmetrical device Nasal Cannula High Flow Oxygenation (HFNCO) app…
Phase: NA • Sponsor: National and Kapodistrian University of Athens • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC
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Scientists probe why belly fat ignores insulin
Knowledge-focused Recruiting nowAdults who gain most of their excess weight in the abdominal area typically do not respond to insulin in the same way as lean adults. Researchers are trying to understand why fat tissue responds differently in people with different body types.
Phase: EARLY_PHASE1 • Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Can vibrating airways and chest walls improve sleep in COPD patients?
Symptom relief CompletedChronic obstructive pulmonary disease (COPD); It is a common, treatable and preventable disease characterized by progressive and irreversible airflow limitation and has systemic effects with respiratory system involvement. Increased respiratory workload, decreased work .
Phase: NA • Sponsor: Saglik Bilimleri Universitesi • Aim: Symptom relief
Last updated Jun 27, 2026 12:24 UTC
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New model could make thyroid surgery safer and more predictable
Knowledge-focused Recruiting nowThe investigators have previously proposed a prediction model for difficult transoral and submental thyroidectomy through a retrospective study. In order to better promote transoral and submental endoscopic approach for thyroid surgery and to set up an appropriate training course…
Sponsor: Shanghai 6th People's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Jaw pain showdown: which injection works best?
Symptom relief CompletedWhich is more effective in the treatment of nonspecific temporomandibular osteoarthritis: platelet-rich plasma (PRP), hyaluronic acid, or triamcinolone acetonide?
Phase: NA • Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC