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127005 trials found · Page 4370 of 6351
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Scientists test new imaging agent to spy on pancreatic tumors
Knowledge-focused Recruiting nowA pilot study to evaluate the expression of PARP-1 in patients with pancreatic neuroendocrine tumors will be conducted. This will be done via the use of a novel PET imaging agent, \[18F\]FluorThanatrace (\[18F\]FTT). A total of 12 patients will be enrolled. Patients will undergo …
Phase 1 • Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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New questionnaire could let breast cancer patients skip some hospital trips
Symptom relief Not yet recruitingThis study aims to develop and prospectively validate a questionnaire to select patients with breast cancer who need to access to hospital for clinical visit during treatment with CDK4/6i, to improve patients' quality of life and reduce burden of hospital accesses.
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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No needles, no drugs: imagined acupuncture tested for Post-Surgery pain
Symptom relief Recruiting nowThe goal of this clinical trial is to evaluate whether imagined acupuncture can reduce postoperative acute pain in adult patients undergoing spinal surgery. The main questions it aims to answer are: Does video-guided imagined acupuncture improve postoperative pain control? Does…
Sponsor: Jingping Wang, MD, Ph.D. • Aim: Symptom relief
Last updated Jun 27, 2026 13:04 UTC
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Could weak muscles mean higher bleeding risk for seniors on blood thinners?
Knowledge-focused Not yet recruitingThis study aims to assess whether reduced muscle mass is associated with an increased risk of bleeding in the elderly receiving direct oral anticoagulant therapy. The researchers will compare the muscle mass of patients who experienced a hemorrhage (case) with that of patients w…
Sponsor: University Hospital, Clermont-Ferrand • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:19 UTC
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New pain block may replace spinal morphine for hysterectomy recovery
Symptom relief CompletedThis study aims to compare the ultrasound-guided transversalis fascia plane (TFP) block and intrathecal morphine for postoperative analgesia in patients undergoing total abdominal hysterectomy (TAH).
Sponsor: Tanta University • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Timing is everything: new study links heart attack delay to dangerous heart rhythms
Knowledge-focused Not yet recruiting1. Evaluate The impact of early versus late presentation on electrocardiographic ventricular repolarization indices. 2. To assess the association between repolarization indices among early, late presentation in relation to in-hospital ventricular arrhythmias, in-hospital MACE, an…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:15 UTC
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Should leftover rectal lesions be removed or watched? small trial aims to find out.
Knowledge-focused Not yet recruitingresidual mucosal lesions in patients with locally advanced rectal cancer after CRT are still confusing for decision to continue follow up or excise. Investigators decided to compare two groups with cCR or nCR with MDT management decision to whether do ESD for this residual lesio…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Nuts vs. disease: Million-Person study seeks answers
Knowledge-focused OngoingThe relationship between nut consumption and the risk of developing non-communicable diseases (NCDs) has been a subject of growing interest. However, the findings from previous studies have been conflicting for some health outcomes, such as type-2 diabetes, and have been underexp…
Sponsor: Institut Investigacio Sanitaria Pere Virgili • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Common blood thinners may calm artery inflammation in at-risk patients
Knowledge-focused Not yet recruitingMany people have a higher chance of getting heart problems. These individuals include people who are very overweight (obesity), have high blood pressure (hypertension), diabetes, or other health concerns. Heart problems often happen because of a condition called atherosclerosis. …
Sponsor: Guy's and St Thomas' NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:40 UTC
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Robot numbing vs. Old-School needle: which scares kids less?
Symptom relief Not yet recruitingThe purpose of this clinical study is to evaluate how different local anesthesia techniques affect pain and anxiety levels in children undergoing dental treatment. Specifically, the study compares traditional syringe-based anesthesia with a computer-controlled local anesthesia sy…
Sponsor: Dicle University • Aim: Symptom relief
Last updated Jun 26, 2026 13:49 UTC
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Stomach study aims to untangle indigestion mystery
Knowledge-focused Recruiting nowBackground: Dyspepsia is a common gastrointestinal complaint globally, affecting approximately 21.8% of the population. Among patients presenting with dyspeptic symptoms, over 80% are diagnosed with functional dyspepsia (FD), while approximately 16% are found to have chronic atr…
Sponsor: The Third Affiliated hospital of Zhejiang Chinese Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Simple physiotherapy program aims to reduce frailty in seniors with heart disease
Symptom relief By invitation onlyThe goal of this clinical trial is to improve the frailty in old patients who have a cardiac disease . Researchers will determine the improvement in the instability and the strength along twelve sessions based on guided exercises and mobility techniques made by physiotherapists.…
Sponsor: Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Sunscreen-Infused silicone stick may boost scar healing after eyelid surgery
Symptom relief Recruiting nowAssess the efficacy of utilizing topical silicone with photoprotection (Improscar Stick® 50) on the quality of healing following upper blepharoplasty, employing the Vancouver and POSAS scales (both patient and observer) over a minimum follow-up period of three months.
Phase 4 • Sponsor: Instituto de Oftalmología Fundación Conde de Valenciana • Aim: Symptom relief
Last updated Jun 27, 2026 09:01 UTC
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New allergy shot for teens shows early promise
Symptom relief OngoingThis is a single-center, open-label, phase Ib clinical study to evaluate the safety, pharmacokinetics and pharmacodynamic characteristics of LP-003 injection in adolescent subjects aged 12-18 years.
Phase 1/2 • Sponsor: Longbio Pharma • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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Garlic supplement shows promise for dialysis patients
Disease control CompletedChronic kidney disease (CKD) is an irreversible condition marked by reduced kidney function or structural abnormalities lasting over three months, affecting a significant portion of the global population. It leads to a cycle of complications including albuminuria, anemia, mineral…
Sponsor: Ain Shams University • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Tennis tech boost for special needs teens
Knowledge-focused OngoingThis study investigates the effect of real-time pose recognition technology on learning tennis skills in individuals with mild to moderate intellectual disabilities. The study compares two training methods: traditional face-to-face tennis instruction and training supported by Rea…
Sponsor: Burdur Mehmet Akif Ersoy University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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New hip block could match standard for Post-Surgery pain relief
Symptom relief Recruiting nowBackground: In recent years, regional anesthesia has become more popular because it can reduce pain and the need for strong pain medications like morphine. For hip surgery, the PENG block is already known to be effective. A newer method, called the iliopsoas plane block (IPB), i…
Sponsor: University of Liege • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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New scale could help prevent bedsores in intensive care
Knowledge-focused CompletedInternational guidelines recommend the use of Pressure Injury risk assessment tools. According to these guidelines, a systematic approach to assessing risk for PI development is essential. Although several tools have been developed, no single clinical pathway is considered superi…
Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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Global ICU rehab study aims to boost recovery for ventilator patients
Knowledge-focused Recruiting nowThis international, multicenter, observational study aims to describe rehabilitation practices in Intensive Care Units (ICUs) worldwide. The primary objective is to provide an overview of current rehabilitation strategies used in ICUs globally. Secondary objectives include asse…
Sponsor: Universita degli Studi di Genova • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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New Two-Tool scope technique aims to remove stuck swallowed objects without surgery
Disease control OngoingWe describe a single-center, retrospective case series (n = 10) for the utilization of dual instruments to extract foreign body at physiological narrowing. Foreign bodies that failed to remove with a single instrument or located in physiological narrowing into the duodenal bulb o…
Sponsor: Shanghai Zhongshan Hospital • Aim: Disease control
Last updated Aug 07, 2026 00:00 UTC