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127426 trials found · Page 4367 of 6372
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Can botox plus physical therapy ease muscle stiffness? new study aims to find out
Symptom relief Not yet recruitingMany people with neurological conditions will experience spasticity, a nonvolitional and uncontrollable tightening and/or spasm of muscles. This can impact the person's functioning and independence in everyday tasks and can contribute to contractures. Spasticity and contracture d…
Sponsor: Technical University of Bern • Aim: Symptom relief
Last updated Jun 26, 2026 15:23 UTC
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New tulip airway device tested for safer breathing support in surgery
Symptom relief Recruiting nowDuring surgery, right after anesthesia is given, the first step to help the patient breathe is to provide breathing support with a mask. This step is very important because if there is a problem with mask ventilation, the anesthesia team must quickly use other methods to help the…
Sponsor: Ayse Zeynep Turan Civraz • Aim: Symptom relief
Last updated Aug 09, 2026 00:00 UTC
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Diet soda alters brain connections, study suggests
Knowledge-focused Not yet recruitingNon-nutritive sweeteners are used as a substitute for simple sugars to improve the palatability of food products without increasing their sugar and calorie content. They represent a global market of 7 billion euros, with an annual growth of 5%. Reducing their consumption therefor…
Sponsor: University Hospital, Clermont-Ferrand • Aim: Knowledge-focused
Last updated Jun 26, 2026 19:10 UTC
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Chew away the pain: gum may soothe braces discomfort
Symptom relief Not yet recruitingThe aim of this study is to determine whether chewing gum can alleviate orthodontic treatment discomfort and improve orthodontic treatment experience. The long-term goal is to enable clinicians to decide whether prescription of chewing gum at the placement of orthodontic applianc…
Phase 3 • Sponsor: West Virginia University • Aim: Symptom relief
Last updated Jun 27, 2026 07:53 UTC
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Simple exercise may ease back pain in college students
Symptom relief Not yet recruitingNonspecific low back pain is a common musculoskeletal problem that also affects many young adults, including university students. It can negatively impact academic performance, daily life, and overall well-being. Research shows that stabilization exercises targeting the lumbar mu…
Sponsor: Mehmet Akif Guler • Aim: Symptom relief
Last updated Jun 26, 2026 19:17 UTC
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Vein fix may ease aching knees, new study hints
Knowledge-focused Not yet recruitingThis study will observe patients with lower limb varicose veins who also have knee pain. Many patients with varicose veins experience swelling, heaviness, or aching in the legs, and some also report pain in or around the knee. Previous studies suggest that venous reflux and poor …
Sponsor: Chengdu University of Traditional Chinese Medicine • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:09 UTC
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Diabetes and periods: new study tracks teen Girls' menstrual health
Knowledge-focused Not yet recruitingTo assess menstraul cycle changes in adolescent girls with diabetes and to find out the various risk factors
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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New imaging technique may reveal hidden lung issues in long COVID patients
Knowledge-focused Not yet recruitingInvestigation of the correlation of CT-morphological changes of the lung compared to regional ventilation distribution on electrical impedance tomography in patients with post-acute-Covid-19 symptoms.
Sponsor: Jan-Christoph Lewejohann • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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800 ARDS patients to be studied for better treatment insights
Knowledge-focused Not yet recruitingThe goal of this observational prospective cohort study is to explore the clinical characteristics, treatment strategies, and outcomes of adult patients with acute respiratory distress syndrome (ARDS) admitted to the medical intensive care unit of Asan Medical Center. The main qu…
Sponsor: Jee Hwan Ahn • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Warm compress and massage may ease Post-Surgery gut issues
Symptom relief CompletedThis randomised controlled trial was designed to determine the effect of early-stage heat application and abdominal massage on patients' gastrointestinal function and mental well-being following hip fracture surgery. The study's hypotheses are as follows: H0: Heat application a…
Sponsor: Cukurova University • Aim: Symptom relief
Last updated Sep 10, 2026 14:00 UTC
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Can a simple scan save kids from paralysis during tumor surgery?
Knowledge-focused Not yet recruitingNeuroblastic tumors (NBTs) develop from neural crest cells that give rise to the sympathetic nervous system. They include neuroblastomas, ganglioneuroblastomas, and ganglioneuromas. They represent approximately 10% of solid tumors in children under 15 years of age. In 15 to 20% o…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:45 UTC
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Can we spot hidden infections in joint replacement fractures?
Knowledge-focused Recruiting nowThis study aims to improve how doctors diagnose infections in patients with broken bones around joint replacements. Currently, there are no clear guidelines to help determine when an infection is present, making treatment decisions difficult. By studying how often infections are …
Sponsor: University of Chicago • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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New imaging technique may predict lung problems in premature babies
Knowledge-focused Recruiting nowThe main hypothesis is that even preterm infants considered "stable" receiving non-invasive ventilation may be at risk of developing BPD due to an inhomogeneous distribution of ventilation. Identifying this characteristic from the first days of life by using EIT could, in the fut…
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC
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Pharmacies as help centers: new study aims to cut hospital visits by tackling social needs
Knowledge-focused Recruiting nowType 1 hybrid effectiveness-implementation study using a quasi-experimental, difference-in-difference (DID) design to deliver a comprehensive social needs screening and navigation program by integrating Community Health Workers (CHWs) into community pharmacies across under-resour…
Sponsor: State University of New York at Buffalo • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Talking therapy for new moms: Nurse-Led chats cut C-Section anxiety
Symptom relief Recruiting nowThis study tests whether a nurse-led "4-step narrative nursing" program can reduce anxiety and improve breastfeeding confidence in mothers who are having a planned or non-emergency cesarean section. What is the problem? About 30-40% of Chinese cesarean mothers feel high anxiety …
Sponsor: Xi Huang • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
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Mothers unite to fight child hunger in pakistan with local solutions
Knowledge-focused Recruiting nowThis project aims to reduce child malnutrition in Pakistan by building on local strengths and practical community solutions. The project focuses on children 7-23 months of age. The investigators will aim to recruit young children between 7-15 months of age, giving the youngest ch…
Sponsor: University of British Columbia • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Can a blood treatment lighten dark gums? new trial investigates
Symptom relief Recruiting nowTo evaluate the usage of microneedling with platelet rich plasma as a gingival depigmentation method in comparison to microneedling alone for pigment intensity reduction. Pre-operative preparation phase includes ultrasonic scaling and oral hygiene instructions for all patients. …
Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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HIIT vs jogging: which workout sharpens your mind faster?
Knowledge-focused By invitation onlyThis study aims to compare the immediate effects of two common types of exercise-moderate-intensity continuous exercise and high-intensity interval training (HIIT)-on attention, alertness, and physiological responses in physically active young adults. Attention and mental alertn…
Sponsor: Qassim University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Hands-On therapy may soothe tennis elbow without drugs
Symptom relief OngoingThis randomised, controlled, double-blind experimental study is designed to evaluate the efficacy of a standardised manual physiotherapy protocol for treating lateral epicondylalgia of the humerus, commonly known as 'tennis elbow'. The study will compare the results for patients …
Sponsor: University of La Laguna • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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New turkish questionnaire could help belgian GPs spot hidden depression
Diagnosis By invitation onlyOur objectives are to determine whether the 4DSQ is valuable for Turkish-speaking patients living in Belgium who face language barriers-meaning they are not fluent in Dutch or French-and have psychological complaints, and to provide better support within the primary healthcare sy…
Sponsor: Universitair Ziekenhuis Brussel • Aim: Diagnosis
Last updated Jun 27, 2026 14:00 UTC