Can botox plus physical therapy ease muscle stiffness? new study aims to find out

NCT ID NCT07160699

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study will test whether combining botulinum toxin (Botox) injections with physical or occupational therapy helps people with spasticity—uncontrollable muscle tightness and spasms. Thirty adults will receive personalized treatment from a team of experts, and researchers will measure if they achieve their own goals and improve movement. The study uses an N-of-1 design, where each person acts as their own control, to see what works best for each individual.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Botulinum neurotoxin type A (Botox) plus physical or occupational therapy

What this could lead to

If it works, this could show that a team-based approach with Botox and therapy helps people with spasticity reach their personal goals and move better.

What could go wrong

This is a small, early study with only 30 people and no comparison group. Results may not apply to everyone, and the benefit over standard care is not yet proven.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Muscle Spasticity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • REHAB Basel

    Basel, 4055, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Royal Hospital for Neuro-disability

    London, West Hill Putney, SW15 3 SW, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••