Can botox plus physical therapy ease muscle stiffness? new study aims to find out
NCT ID NCT07160699
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study will test whether combining botulinum toxin (Botox) injections with physical or occupational therapy helps people with spasticity—uncontrollable muscle tightness and spasms. Thirty adults will receive personalized treatment from a team of experts, and researchers will measure if they achieve their own goals and improve movement. The study uses an N-of-1 design, where each person acts as their own control, to see what works best for each individual.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Botulinum neurotoxin type A (Botox) plus physical or occupational therapy
- What this could lead to
- If it works, this could show that a team-based approach with Botox and therapy helps people with spasticity reach their personal goals and move better.
- What could go wrong
- This is a small, early study with only 30 people and no comparison group. Results may not apply to everyone, and the benefit over standard care is not yet proven.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for SPASTICITY are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
REHAB Basel
Basel, 4055, Switzerland
-
Royal Hospital for Neuro-disability
London, West Hill Putney, SW15 3 SW, United Kingdom
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can botox doses be optimized for kids with cerebral palsy?
- Electric suit aims to ease spasticity and boost balance in kids with cerebral palsy
- Spinal zaps may quiet overactive muscles in kids with cerebral palsy
- Heat pulses to nerves may loosen stiff elbows after brain injury
- Enzyme injection could loosen stiff muscles in stroke survivors
- Freezing pain away: yale tests Nerve-Blocking procedure for Long-Term relief