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116076 trials found · Page 4317 of 5804
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New prism device may help one-eyed pedestrians avoid collisions
Symptom relief TerminatedThe investigators are developing an assistive device, known as multiplexing prism that expands the field of view for individuals with acquired monocular vision (loss of an eye). The investigators will test the efficacy of the prism in improving the detection of colliding pedestri…
Phase: NA • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Symptom relief
Last updated Jul 11, 2026 00:00 UTC
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No antibiotics before prostate biopsy? new study checks safety
Knowledge-focused CompletedThis study is a prospective cohort study to delineate the infective outcomes and incidence after transperineal prostate biopsy with no antibiotic prophylaxis, compared to the existing data on outcomes on patients receiving transperineal prostate biopsy with antibiotic prophylaxis…
Phase: NA • Sponsor: Chinese University of Hong Kong • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Vitamin K2 shows promise for childhood eczema
Symptom relief Completedinvestigate the effectiveness and safety of adding vitamin K2 at a dose of 45 mg/day for 12 weeks to conventional therapy for paediatric patients with moderate to severe atopic dermatitis according to SCORAD score
Phase: NA • Sponsor: October 6 University • Aim: Symptom relief
Last updated Jun 27, 2026 12:31 UTC
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Can dead teeth be brought back to life? new study tests regeneration vs. standard cleaning
Disease control CompletedIt was to compare clinically between the success of the primary endodontic treatment, regeneration, and only cleaning and shaping in necrotic mature first premolars with apical periodontitis
Phase: NA • Sponsor: Ain Shams University • Aim: Disease control
Last updated Jun 27, 2026 13:01 UTC
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New combo offers longer pain relief after hernia surgery
Symptom relief CompletedThis study will evaluate the efficacy and safety of intrathecal non-preservative-free morphine and its effect on pain in patients undergoing unilateral inguinal hernia surgeries.
Phase: PHASE3 • Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 27, 2026 08:02 UTC
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New anesthetic combo may help hernia patients go home sooner
Symptom relief CompletedBackground: In the context of day-case surgery, the optimal spinal anesthetic should give immediate and effective anesthesia for an appropriate period, followed by rapid regression of sensory and motor blocking, rapid bladder voiding, and little residual effects to allow for earl…
Phase: PHASE4 • Sponsor: Theodor Bilharz Research Institute • Aim: Symptom relief
Last updated Jun 27, 2026 08:01 UTC
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Promising cancer drug trial halted after just one patient
Disease control TerminatedAn international multi-centre, open, randomised, parallel-group phase II study comparing adjuvant treatment with 177Lu-DOTATATE to best supportive care in patients after complete surgical removal of neuroendocrine liver metastases. In this study, adjuvant treatment with 177Lu-DO…
Phase: PHASE2 • Sponsor: Imperial College London • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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Could a saliva test spot gum and implant disease early?
Knowledge-focused CompletedPeri-implant diseases, encompassing peri-implant mucositis and peri-implantitis, are biologically driven inflammatory conditions that threaten the long-term success of dental implants. The microbial signatures and their metabolic products have prompted growing interest in salivar…
Sponsor: Istanbul Medipol University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Can dancing online cut Alzheimer's risk in down syndrome?
Symptom relief CompletedThe investigators are assessing acceptability, appropriateness, and feasibility of an remote choreographed exercise intervention using validated scales alongside qualitative data among young adults with Down Syndrome. Participants will take part in a 12-week exercise program with…
Phase: NA • Sponsor: University of Kansas Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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New drug STP938 tested in patients with incurable cancers
Disease control Recruiting nowThe Phase 1a part of the study is a dose escalation of STP938 as a monotherapy. The Phase 1b part of the study is a safety expansion cohort of STP938 as a monotherapy.
Phase: PHASE1 • Sponsor: Step Pharma, SAS • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Can a smartphone app help young adults stop self-harming?
Symptom relief CompletedThis is a feasibility trial of a digital mental health intervention aimed at young adults (ages 18-25) with nonsuicidal self-injury and who are not currently engaged in mental health treatment. We will pilot three arms: a self-guided DMHI, the DMHI with low-intensity coaching, or…
Phase: NA • Sponsor: Northwestern University • Aim: Symptom relief
Last updated Jun 27, 2026 12:07 UTC
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Mountain rescue under the microscope: does thin air hurt patient care?
Knowledge-focused CompletedRescue services in mountainous regions are frequently called to missions at altitudes \>3000 m. Under the difficult conditions of acute exposure to altitude, the crews then have to undertake demanding medical and rescue measures. Previous studies in non-medical personnel, such as…
Phase: NA • Sponsor: Insel Gruppe AG, University Hospital Bern • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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New device aims to prevent bedsores from breathing tubes
Symptom relief Recruiting nowThe aim of this study is to assess the benefits of using the Anchorfast device in reducing complications associated with intubation tube fixation, in terms of the rate of pressure ulcer development, the rate of intubation tube mobilization and the rate of VAP occurrence. If the h…
Phase: NA • Sponsor: Hopital Foch • Aim: Symptom relief
Last updated Jun 27, 2026 13:06 UTC
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Can a brain zapping helmet help treat anorexia?
Symptom relief CompletedThis study looks at adults with restrictive eating disorders who are currently receiving outpatient treatment for their eating disorder to examine whether a new brain stimulation technique called non-invasive transcranial direct current stimulation (tDCS) can enhance brain traini…
Phase: PHASE1 • Sponsor: University of Minnesota • Aim: Symptom relief
Last updated Jun 27, 2026 14:01 UTC
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FSHD patients unite: new registry aims to accelerate research and care
Knowledge-focused Recruiting nowBetterLife FSHD is a registry platform built to support people living with FSHD. It connects patients with personalized resources, tools, and research opportunities that match their health experiences and needs. At the same time, BetterLife collects secure health and experience d…
Sponsor: FSHD Society • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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Experimental cancer drug tested in early trial, but study stopped early
Disease control TerminatedThis clinical trial is studying advanced solid tumors. Solid tumors are cancers that start in a part of your body like your lungs or liver instead of your blood. Once tumors have grown bigger in one place but haven't spread, they're called locally advanced. If your cancer has spr…
Phase: PHASE1 • Sponsor: Seagen, a wholly owned subsidiary of Pfizer • Aim: Disease control
Last updated Jul 09, 2026 00:00 UTC
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Relaxation boosts exercise benefits for high blood pressure
Disease control CompletedThe study is a randomized controlled trial. The purpose of study is to compare the additive effects of Jacobson's progressive muscle relaxation technique with aerobic exercise versus aerobic exercise on cardiopulmonary parameters including systolic and diastolic blood pressure, h…
Phase: NA • Sponsor: Foundation University Islamabad • Aim: Disease control
Last updated Jun 26, 2026 17:27 UTC
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New Artery-Blocking technique could make rectal surgery safer
Disease control Recruiting nowThe present study will investigate the safety of inferior mesenteric artery embolization prior to rectal surgery, according to IDEAL recommendations (Lancet 2009). It aims to assess the safety of endovascular embolization of the inferior mesenteric artery prior to surgery in pati…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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Anemia type may predict surgery danger
Knowledge-focused Recruiting nowThe goal of this observational study focuses on the effect of different preoperative anemia status on perioperative complications in patients under moderate- to high-risk surgery. Different anemia types conclude iron-deficiency anemia(IDA), anemia of chronic disease/anemia of inf…
Sponsor: Peking Union Medical College Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Liver donors may skip the drain: new study tests safety.
Knowledge-focused Recruiting nowProphylactic abdominal drain placement after donor hepatectomy has been a common or even mandatory practice in most transplant centers. This serves to monitor the occurrence of post-operative intra-abdominal bleeding and is used for the detection and drainage of any bile leakage.…
Phase: NA • Sponsor: Marengo Asia Hospitals • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC