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127005 trials found · Page 4317 of 6351
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PCOS and fibromyalgia: is there a hidden link?
Knowledge-focused Not yet recruitingThe primary objective was to determine the prevalence of fibromyalgia in women with PCOS and to examine the relationship between fibromyalgia and psychological status (depression and anxiety). Secondary objectives were to explore the potential link between fibromyalgia and insuli…
Sponsor: Ufuk University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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New scan could reveal hidden heart inflammation in common heart failure
Knowledge-focused Recruiting nowThe purpose of this study is to assess the performance of 68Ga- FAPI PET in heart failure with preserved ejection fraction (HFpEF)
Phase 2 • Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jul 10, 2026 00:00 UTC
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Scientists probe hidden Hormone's role in prediabetes
Knowledge-focused Recruiting nowWe recently demonstrated that blockade of Glucagon-Like Peptide-1's (GLP-1) receptor (GLP1R) results in changes in islet function without changes in circulating GLP-1. These effects are more pronounced in people with early type 2 diabetes (T2DM) in keeping with increased expressi…
Phase 2 • Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Which anesthesia drug protects the heart better in cancer surgery?
Symptom relief Not yet recruiting\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_ Background : Major abdominal cancer surgery is among the most invasive procedures, often associated with extensive tissue damage, severe postoperative pain, and delayed recovery. Inadequate pain ma…
Phase 4 • Sponsor: Assiut University • Aim: Symptom relief
Last updated Jun 27, 2026 07:54 UTC
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Light-Based device could spot kidney trouble in tiniest babies
Knowledge-focused Recruiting nowThe primary objective of this study is to describe the pattern of renal tissue oxygen saturation (SrSO2) using near-infrared spectroscopy (NIRS) in premature infants \<30 weeks gestational age. The secondary objective of this study is to evaluate prenatal and postnatal risk facto…
Sponsor: NYU Langone Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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New app aims to boost mental strength in hospitalized teens with cancer
Symptom relief Not yet recruitingThis study will develop and evaluate a mobile-based co-design intervention (CesiKids) to enhance psychosocial resilience in hospitalized adolescents aged 12-18 diagnosed with cancer. The program will be created using Bronfenbrenner's Ecological Systems Theory and designed in coll…
Sponsor: Eskisehir Osmangazi University • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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New Non-Invasive exercise test could replace catheters for Heart-Lung diagnosis
Diagnosis Recruiting nowCPETecho is progressively employed in diagnostic settings for pathophysiological detection, offering comprehensive assessment of both pulmonary and cardiac functions. This technique evolves from its invasive counterpart, where a diagnostic catheter is employed for hemodynamic mon…
Sponsor: Ziekenhuis Oost-Limburg • Aim: Diagnosis
Last updated Jun 27, 2026 08:04 UTC
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MRI reveals hidden jaw disc tears in 282 patients
Knowledge-focused CompletedTo evaluate the presence of TMJ disc perforation on MRI and investigate its associations with internal disc derangements, disc configuration, condylar bone marrow signal patterns, joint effusion, and demographic or clinical variables such as age, sex, dental status, and pain seve…
Sponsor: Recep Tayyip Erdogan University Training and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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New Light-Based test could predict best treatment for leg artery disease
Knowledge-focused Recruiting nowThe goal of this study is to better understand how blood flows and how oxygen is utilized in the lower limbs of people who suffer from peripheral artery disease. This study will also assess how these factors affect treatment outcomes. Specific aims include: Aim 1: Utilize BB-NI…
Sponsor: The University of Texas at Arlington • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Could melatonin help heal your gums?
Disease control By invitation onlymelatonin loaded in injectible platelet rich fibrin in treatment of periodontitis
Phase 4 • Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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New study aims to find best way to save choking babies
Knowledge-focused CompletedForeign body airway obstruction (FBAO, choking) is a life-threatening emergency requiring time-sensitive treatment to prevent severe injury or deaths. Traditional treatments taught in first aid courses include abdominal thrusts, back blows, and chest compressions or thrusts. Curr…
Sponsor: University of Calgary • Aim: Knowledge-focused
Last updated Sep 10, 2026 09:00 UTC
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Inflammation may change how your body handles medications
Knowledge-focused Recruiting nowPro-inflammatory cytokines, which are elevated in pro-inflammatory disease states (e.g., type II diabetes mellitus \[T2DM\], irritable bowel diseases \[IBD\], and end stage renal disease \[ESRD\]) have been shown to inhibit hepatic drug-metabolizing enzymes, including members of …
Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Brush vs bur: which tool erases gum stains best?
Symptom relief Recruiting nowGingival hyperpigmentation, particularly of melanin origin, can pose significant aesthetic concerns, especially among patients with a high smile line. Several depigmentation techniques have been proposed to manage this condition, including scalpel surgery, electrosurgery, cryothe…
Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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Do cancer patients regret their surgery? new study investigates
Knowledge-focused Recruiting nowPatients undergoing major abdominal surgery often have to make complex decisions about their treatment, where risks, benefits and possible complications must be considered. Limited health literacy and unmet expectations can make this process difficult and may increase the risk of…
Sponsor: Rigshospitalet, Denmark • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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Virtual reality offers Drug-Free pain relief for seniors during wound care
Symptom relief Recruiting nowThis study will test whether immersive virtual reality (iVR) can reduce pain and discomfort during wound care for residents living in long-term care (LTC). Pressure ulcers are common and painful among older adults, and dressing changes often cause additional distress. Up to 20 r…
Sponsor: McGill University • Aim: Symptom relief
Last updated Jun 27, 2026 09:10 UTC
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Can simple blood tests predict lung Flare-Ups?
Knowledge-focused Recruiting nowBronchiectasis, also referred to as non-cystic fibrosis (non-CF) bronchiectasis, is a chronic respiratory disease defined by abnormal and irreversible dilatation of the bronchi (1). Dilatation of the bronchial lumen predisposes to infection (2). Recurrent infection and airway inf…
Sponsor: Sohag University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Brain zaps tested for 'Healthy Eating' obsession
Knowledge-focused Recruiting nowOrthorexia Nervosa (ON); is a condition characterized by individuals being overly focused on healthy eating habits, constantly checking and classifying the foods they will consume. ON has not yet been clinically defined as an eating disorder or in a different category, and has no…
Sponsor: Istanbul Medipol University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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Protein PHGDH may predict immunotherapy success in colorectal cancer
Knowledge-focused CompletedThis study aims to evaluate the expression characteristics of PHGDH in tumor tissues based on the clinical data and pathological tissue samples of colorectal cancer patients who have previously received immunotherapy, and to analyze its correlation with patients' clinical feature…
Sponsor: West China Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
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Neck braces may be unnecessary for stable fractures, study suggests
Knowledge-focused Recruiting nowBackground and Purpose: Neck fractures affect over 1,100 people in Sweden each year, with the majority being frail older adults. Most neck fractures are stable and therefore treated without surgery, typically using a rigid collar. However, the collar only limits neck movement by…
Sponsor: Uppsala University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Digital precision vs. steady hands: which places orthodontic screws better?
Disease control CompletedThis randomized split-mouth clinical trial aims to compare the accuracy and clinical outcomes of CAD/CAM 3D-printed surgical guides with the conventional free-hand technique for orthodontic miniscrew placement in the posterior maxilla. Each participant will receive miniscrew plac…
Sponsor: Can Tho University of Medicine and Pharmacy • Aim: Disease control
Last updated Jul 15, 2026 00:00 UTC