Scientists probe hidden Hormone's role in prediabetes
NCT ID NCT06967558
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how a hormone called GLP-1, made in the pancreas, helps control blood sugar in people with prediabetes. Researchers will give a drug that blocks GLP-1 to see how it changes insulin and glucagon release. The goal is to understand why some people with prediabetes go on to develop type 2 diabetes. About 60 adults with stable weight and no diabetes will take part.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Exendin 9-39 (a GLP-1 receptor blocker)
What this could lead to
If successful, this could reveal why some people with prediabetes develop type 2 diabetes, pointing toward new prevention strategies.
What could go wrong
This is a small, early-phase study focused on understanding biology, not testing a treatment. Results may not lead to direct patient benefits.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Mayo Clinic in Rochester
RECRUITINGRochester, Minnesota, 55905, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••