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116076 trials found · Page 4122 of 5804
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Preeclampsia may weaken the heart during pregnancy, new study finds
Knowledge-focused CompletedThis is a prospective observational study conducted at the Maternity and Neonatology Center of Tunis to evaluate cardiac diastolic function in women with preeclampsia compared with normotensive pregnant women. A total of 80 pregnant women in the third trimester were enrolled, inc…
Sponsor: University Tunis El Manar • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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New nasal spray could ease Kids' surgery fears
Symptom relief Recruiting nowFor pediatric patients undergoing general anesthesia, poor anesthesia induction compliance often has adverse effects on individual behavior in the early postoperative period. Dexmedetomidine can reduce the cardiovascular responses and postoperative mental adverse reactions caused…
Phase: PHASE4 • Sponsor: Second Affiliated Hospital of Wenzhou Medical University • Aim: Symptom relief
Last updated Jun 27, 2026 08:01 UTC
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Ultrasound peek at stroke spasticity could guide rehab
Knowledge-focused CompletedIntroduction A large number of stroke patients develop spasticity in the upper and lower extremities, which is one of the clinical signs of damage to motor neuron 1, causing abnormal postures and movement patterns due to motor neuron hyperexcitability and rheological alterations …
Sponsor: Universidad de La Frontera • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Grip strength may predict which asthma inhaler works best for you
Knowledge-focused CompletedAsthma is a chronic respiratory disease characterized by variable airway obstruction. Inhaled therapies are the cornerstone of asthma management, and selecting the appropriate inhaler device is essential for effective treatment. Among available devices, metered dose inhalers (MDI…
Phase: NA • Sponsor: Bugra Kerget • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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New gel shows promise for dark skin patches
Symptom relief CompletedThe purpose of this study is to demonstrate the safety and efficacy of Sirolimus 0.2% topical gel for patients with Acanthosis Nigricans
Phase: PHASE2 • Sponsor: Narrows Institute for Biomedical Research • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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Gut bugs linked to early menopause?
Knowledge-focused OngoingIn order to study the community profile of the intestinal microbiome in women with ovarian dysfunction, as well as the relationship between the changes in the intestinal microbiota and sex hormones, this study recruited 30 women with ovarian dysfunction and 30 healthy women. Sequ…
Phase: EARLY_PHASE1 • Sponsor: Songling Zhang • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Simple mouth exercises may help preterm babies feed sooner
Symptom relief Recruiting nowThis is a randomized controlled experimental study evaluating the effects of oral motor intervention and chronobiological approach to feeding model applied to preterm infants on feeding readiness, transition to total oral feeding and body weight.
Phase: NA • Sponsor: Aydin Adnan Menderes University • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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New combo treatment aims to turn back the clock on aging skin
Symptom relief CompletedEnhancing Skin Rejuvenation A Single-Blind, Randomized Control Study on the Combined Efficacy of Aerolase 1064 nm YAG Laser and Exosomes Derived from Umbilical Cord Mesenchymal Stem Cells
Phase: PHASE3 • Sponsor: Laser Beamer Skincare • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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Could a common antibiotic replace stronger ones for severe pneumonia?
Knowledge-focused CompletedSevere community-acquired pneumonia (CAP) and community-acquired aspiration pneumonia (CAAP) are common reasons for adult emergency department visits and subsequent admission to the intensive care unit (ICU). Three bacteria are primarily implicated in this type of pneumonia: Stre…
Sponsor: Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer • Aim: Knowledge-focused
Last updated Jul 09, 2026 00:00 UTC
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Knee pain in young athletes linked to hip and core weakness
Knowledge-focused CompletedThis cross-sectional observational study investigated the relationships among dynamic Q angle, core muscle endurance, hip flexibility, and lower extremity functional status in elite adolescent athletes with and without patellofemoral pain syndrome (PFPS). A total of 75 track-and-…
Sponsor: Eastern Mediterranean University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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Anesthesia before age 4: lasting brain impact?
Knowledge-focused CompletedThis study aims to evaluate the potential long-term cognitive effects of general anesthesia administered before the age of 4. Specifically, it investigates executive functions-including inhibition, working memory, and cognitive flexibility-in children aged 9 to 10 years. A second…
Sponsor: University Hospital, Caen • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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New blood markers may help predict heart trouble in diabetes patients
Knowledge-focused CompletedType 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by impaired insulin action and increased cardiometabolic risk. Visceral adiposity, insulin resistance, systemic inflammation, and dyslipidemia play key roles in the development of cardiovascular disease…
Sponsor: Tokat Gaziosmanpasa University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Can a single pill cut opioid use after hip surgery?
Symptom relief Recruiting nowThe primary objective of this study is to compare total narcotic intake standardized via milligram morphine equivalents between duloxetine and placebo cohorts after a total hip arthroplasty.
Phase: PHASE4 • Sponsor: University of Miami • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC
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Gentle massage and bed exercises may ease gut troubles for Tube-Fed patients
Symptom relief CompletedPalliative care is a special type of medical care that focuses on providing support and improving the quality of life for individuals facing life-threatening illnesses. Nursing care for patients receiving enteral nutrition includes interventions that facilitate nutrition, increas…
Phase: NA • Sponsor: Kahramanmaras Sutcu Imam University • Aim: Symptom relief
Last updated Jun 27, 2026 14:01 UTC
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Brazil launches nationwide effort to curb superbugs in hospitals
Knowledge-focused OngoingAntimicrobial resistance is a major global public health challenge, leading to increased morbidity, mortality, and healthcare costs. Antimicrobial Stewardship Programs (ASPs) are recognized as an effective strategy to improve the appropriate use of antimicrobials and to reduce th…
Phase: NA • Sponsor: Hospital Alemão Oswaldo Cruz • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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New school program aims to boost mental health for immigrant girls
Knowledge-focused OngoingThe goal of this study is to see if VOCES-NUEVAS, a school-based program for newcomer girls from Latin America, is helpful and easy to use. The main questions the investigators want to answer are: * Is VOCES-NUEVAS a good fit for newcomer girls in schools? * Does it help improve…
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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New portable device could simplify testing for Birth-Related anal injuries
Diagnosis CompletedCurrently, high resolution anorectal manometry (HDARM) is used as gold standard to measure anal sphincter pressures in women who have sustained a third or fourth degree perineal tears (obstetric anal sphincter injuries). This test is performed to help advise patients on future pr…
Phase: NA • Sponsor: King's College Hospital NHS Trust • Aim: Diagnosis
Last updated Jun 27, 2026 12:08 UTC
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Morning or evening? stanford tests best time for insomnia therapy
Symptom relief Recruiting nowRepetitive transcranial magnetic stimulation (rTMS) has shown to be a promising technique for improving insomnia symptoms and sleep quality. However, the impact of circadian rhythmicity on rTMS sessions and its potential influence on insomnia therapy remains unclear. Moreover, th…
Phase: NA • Sponsor: Stanford University • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Rosemary oil may sharpen memory, small trial hints
Symptom relief OngoingAromatherapy is one of the complementary therapies that is carried out through essential oils. The essential oil of Rosmarinus Officinalis L. (rosemary) has been gaining attention in aromatherapy research, as studies have shown that the use of this oil is one of the promising non…
Phase: NA • Sponsor: Federal University of Paraíba • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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Virtual reality headsets calm anxious Moms-to-Be during fetal monitoring
Symptom relief CompletedAim: This randomized controlled trial aimed to compare the effectiveness of virtual reality and progressive muscle relaxation exercise in reducing anxiety during the non-stress test (NST) and to evaluate their effects on maternal physiological parameters in high-risk pregnant wo…
Phase: NA • Sponsor: Istanbul University - Cerrahpasa • Aim: Symptom relief
Last updated Jun 27, 2026 14:02 UTC