Morning or evening? new study tests best time for cancer pill.

NCT ID NCT07252726

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study is testing whether taking endocrine therapy in the morning or evening makes a difference for people with metastatic breast or prostate cancer. Fifty participants will be randomly assigned to take their medication either within an hour of waking or within an hour of bedtime. The main goal is to see if a larger trial is possible, while also looking at quality of life, side effects, and how well the treatment works.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

endocrine therapy (CDK4/6 inhibitor or androgen receptor pathway inhibitor)

What this could lead to

If successful, this could show that simply changing the time of day you take your medication improves quality of life and treatment tolerability.

What could go wrong

This is a small pilot study with only 50 participants, so results may not apply broadly. The main goal is to see if a larger trial is possible, not to prove effectiveness.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast carcinoma breast neoplasm hormone receptor-positive breast cancer metastatic prostate carcinoma Neoplasm Metastasis prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Saskatoon Cancer Centre

    NOT_YET_RECRUITING

    Saskatoon, Saskatchewan, Canada

  • The Ottawa Hospital Cancer Centre

    RECRUITING

    Ottawa, Ontario, K1H 8L6, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Waterloo Regional Health Network

    RECRUITING

    Kitchener, Ontario, Canada