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127005 trials found · Page 4063 of 6351
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Which ventilation method best protects ARDS lungs? small study aims to find out
Knowledge-focused Not yet recruitingBackground: In patients with acute hypoxemic respiratory failure or ARDS, mechanical ventilation is often required. Two common strategies are pressure support ventilation (PSV), which allows spontaneous breathing, and volume-controlled ventilation (VCV), which delivers fixed tid…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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New MRI scan could pinpoint epilepsy hotspots without surgery
Knowledge-focused Not yet recruitingEpilepsy is a common neurological disorder with an incidence of 1%. Although many anti-seizure medications are available, about 30% of patients are resistant to drug treatments. Epilepsy surgery is an effective treatment for some of these patients. It involves removing the brain …
Sponsor: Fondation Ophtalmologique Adolphe de Rothschild • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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Could a nail polish treat psoriasis? small trial tests tofacitinib lacquer
Symptom relief Not yet recruitingTo evaluate the efficacy and safety of topical 2% tofacitinib nail lacquer in nail psoriasis, using the NAPSI and DLQI scales before and after 26 weeks of treatment.
Phase 2 • Sponsor: Hexsel Dermatology Clinic • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC
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New anesthesia combo may reduce risks during chest surgery
Symptom relief Not yet recruitingTitle: A Clinical Study Comparing Two Anesthesia Methods for Chest Surgery Why is this study being done? Chest surgeries (like lung surgery) require safe and stable anesthesia. Currently, a drug called propofol combined with an opioid painkiller (alfentanil) is commonly used. Ho…
Phase 4 • Sponsor: The First Affiliated Hospital of Xinxiang Medical College • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC
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Long fasting times may raise confusion risk after surgery
Knowledge-focused Not yet recruitingPostoperative delirium is a common and serious complication after surgery, especially in older patients, and is associated with prolonged hospital stay and worse recovery. Fasting before and after surgery is a routine part of perioperative care; however, prolonged fasting may neg…
Sponsor: Akdeniz University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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New Omega-3 pill could boost heart health better than standard fish oil
Disease control Not yet recruitingThis study is a clinical trial designed to compare two forms of omega-3 supplements in adults with mixed dyslipidemia. Mixed dyslipidemia is a condition in which blood fat levels, such as triglycerides and cholesterol, are not within the recommended range and may increase the ris…
Sponsor: Fundación del Caribe para la Investigación Biomédica • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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New study tests community talks and support to boost mood in seniors
Symptom relief Not yet recruitingThis study is conducted to assess the effectiveness of a community intervention programme on improving well-being, levels of distress, and loneliness in older adults (aged 55 years old and above), who have symptoms of depression. Social Service Agencies (SSAs) will conduct focal…
Sponsor: National Healthcare Group Polyclinics • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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Hidden OCD symptoms may complicate addiction recovery
Knowledge-focused Not yet recruitingThis observational, cross-sectional case-control study evaluates obsessive-compulsive symptoms among adults with substance use disorder compared with a demographically similar control group without substance use disorder. Patients aged 18-50 years attending the addiction manageme…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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New ultrasound trick could spot fetal anemia faster
Diagnosis Not yet recruitingFetal anemia one of serious fetal problems that may lead in sever cases to fetal demise early detection and precise intervention safe fetal life , traditional evaluation the severity and need of blood transfusion done by middle cerebral artery peak systolic velocity in doppler wa…
Sponsor: Assiut University • Aim: Diagnosis
Last updated Jun 27, 2026 09:04 UTC
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Chill out after knee surgery: could cooling be the key to less pain?
Symptom relief Not yet recruitingThis study investigates whether cooling the knee after total knee replacement surgery can reduce pain and improve early recovery. After surgery, patients are randomly assigned to one of three groups: cooling with a liquid cooling bandage, cooling with an ice pack, or standard pos…
Sponsor: Clinical Center of Vojvodina • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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New decision aid aims to reduce surgery regret for rhinitis patients
Knowledge-focused Recruiting nowThis study is a prospective randomized controlled trial that aims to enroll 158 patients diagnosed with chronic hypertrophic rhinitis who are candidates for inferior turbinate surgery. Participants will be randomly assigned to either the "standard group" or the "PDA group." The s…
Sponsor: Taipei Medical University Shuang Ho Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
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New tool could help doctors spot muscle problems after stroke
Knowledge-focused Not yet recruitingIn this study, the validity and reliability of the Hypertonia Assessment Tool (HAT), which has previously been validated in the pediatric cerebral palsy (CP) population, will be evaluated in adult individuals who have experienced a stroke. The HAT is a specific clinical instrumen…
Sponsor: Fatih Sultan Mehmet Training and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Heel fracture study: which surgery works best?
Disease control Not yet recruitingThis study is to compare clinical outcome of Sanders type III or IV intra-articular calcaneal fracture treated with open reduction and internal fixation (ORIF) versus ORIF and primary subtalar arthrodesis (PSTA).
Sponsor: Ahmed Gamal Ibrahim Saleh • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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New study tests best way to push during labor to cut pain and fatigue
Symptom relief OngoingThe Effect of Pushing Techniques Used During Childbirth on Women's Labor Duration, Pain, and Fatigue Levels
Sponsor: Cumhuriyet University • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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Laser plus injection may improve scar healing
Symptom relief Recruiting nowFacial scars are frequently deemed unpleasant and can profoundly impact a patient's psychological health. This study compares the effectiveness, safety, and capacity to speed up scar healing in the maxillofacial region between fractional carbon dioxide (CO₂) laser therapy alone a…
Phase 2 • Sponsor: Misr University for Science and Technology • Aim: Symptom relief
Last updated Jun 27, 2026 11:01 UTC
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Heart Patients' pill habits under the microscope in new study
Knowledge-focused Not yet recruitingThis study aims to assess medication adherence and the appropriateness of prescribed medications among patients admitted to the Coronary Care Unit (CCU). The study will use the Medication Appropriateness Index (MAI) to evaluate the suitability of prescribed medications and the Be…
Sponsor: AlFayhaa General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Gum disease breakthrough? blood concentrate may regrow bone without surgery
Disease control Recruiting nowThis study aims to clinically and radiographically evaluate the adjunctive effect of injectable platelet-rich fibrin (i-PRF) used in combination with a minimally invasive non-surgical technique for the regenerative treatment of intrabony periodontal defects.
Sponsor: October 6 University • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Mind over knee pain? study probes link between worry and osteoarthritis suffering
Knowledge-focused CompletedKnee osteoarthritis is a common degenerative joint disease in which pain severity often does not fully correspond with radiographic disease severity. Psychological processes such as rumination and worry may contribute to differences in pain perception and functional limitation am…
Sponsor: Fatih Sultan Mehmet Training and Research Hospital • Aim: Knowledge-focused
Last updated Sep 03, 2026 00:00 UTC
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Dancers' bladder health under the spotlight
Knowledge-focused By invitation onlyThe purpose of this study is to describe the prevalence of Urinary Incontinence amongst professional and pre-professional dancers and its relation to Low Energy Avaliability
Sponsor: University of Siena • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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Knee angle may predict injury risk in young volleyball athletes
Knowledge-focused CompletedThis observational study aims to examine the relationship between frontal plane knee projection angle, dynamic balance, agility performance, and ankle dorsiflexion mobility in adolescent female volleyball players. Frontal plane knee projection angle will be assessed during a sing…
Sponsor: Sinop University • Aim: Knowledge-focused
Last updated Jul 19, 2026 00:00 UTC