Could a nail polish treat psoriasis? small trial tests tofacitinib lacquer
NCT ID NCT07313072
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This Phase 2 trial tests a daily nail lacquer containing 2% tofacitinib for nail psoriasis. Ten adults with nail psoriasis will apply the lacquer at home for 26 weeks. Researchers will measure changes in nail appearance using the Nail Psoriasis Severity Index and quality of life using a dermatology questionnaire.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- 2% tofacitinib nail lacquer
- What this could lead to
- If it works, this could offer a new topical option for people with nail psoriasis, potentially improving nail appearance and quality of life without systemic drugs.
- What could go wrong
- This is a very small early-phase trial with only 10 participants, so results may not apply broadly. The treatment may not work or could cause skin irritation.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Other studies related to the condition(s) this trial covers.