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127005 trials found · Page 3970 of 6351
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New PET tracer aims to illuminate hidden HER2 tumors
Diagnosis Recruiting nowThe purpose of this study is to determine if the radiotracer, \[68Ga\]Ga-ABY-025, used for PET imaging can help us better identify and visualize lesions or tumors, in patients who are receiving standard of care therapy HER2+ cancers.
Early phase 1 • Sponsor: Vanderbilt-Ingram Cancer Center • Aim: Diagnosis
Last updated Jun 27, 2026 12:30 UTC
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Could a simple gas help stroke patients? early trial launches
Symptom relief Recruiting nowThe purpose of this study is to determine the safety and feasibility of using inhaled nitric oxide (iNO) in patients undergoing intra-arterial mechanical thrombectomy (blood clot extraction or IAMT) for treatment of acute ischemic (non-bleeding) stroke (AIS).
Phase 1 • Sponsor: Wake Forest University Health Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Could a Warm-Up device save breast reconstruction skin?
Symptom relief Not yet recruitingThe goal of this clinical trial is to evaluate the use of the Plexaa preconditioning device (BLOOM43) in patients undergoing reconstructive breast surgery for breast cancer. This study aims to understand a participant's experience of the device, including its usability and accept…
Sponsor: Plexaa Ltd • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC
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Community navigators aim to ease stress in underserved communities
Symptom relief Recruiting nowThis pilot study tests the feasibility and preliminary impact of a protocolized promotora-led navigation intervention to improve behavioral health access among Latinx and Native American underserved adults. The study is embedded within a community cultural center, leveraging a tr…
Sponsor: University of California, Riverside • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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New registry tracks Real-World use of PFIC drug odevixibat
Disease control Recruiting nowThis registry-based study will collect information from people with Progressive Familial Intrahepatic Cholestasis (PFIC) who take odevixibat (Bylvay) as part of routine clinical care in China. PFIC is a rare genetic liver disease that affects bile secretion and can cause bile ac…
Sponsor: Ipsen • Aim: Disease control
Last updated Sep 02, 2026 00:00 UTC
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New knee shot aims to ease arthritis pain in early trial
Symptom relief By invitation onlyThis is a randomized, double-blind, placebo-controlled dose-escalation study designed to evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary efficacy of intra-articular injection of RAB001 in participants with knee osteoarthritis (KOA). The study consists o…
Phase 1 • Sponsor: ZhongShan LaiBo RuiChen BioMedicine Co.,Ltd. • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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Which works better for bone infections: cleaning or replacing hardware?
Disease control CompletedThis study aims to compare the clinical outcomes of debridement, antibiotics, and implant retention (DAIR) and implant removal/replacement methods used in the treatment of fracture-related infections, and to determine the infection-free fracture healing rates and the factors affe…
Sponsor: Antalya Health Sciences University • Aim: Disease control
Last updated Jul 09, 2026 00:00 UTC
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Growth factor gel may speed skin recovery after laser resurfacing
Symptom relief Recruiting nowariessence is intended to be used as a viscous, leave-on solution designed for topical application to the face. It is intended to be used following non-medical cosmetic procedures, performed by licensed healthcare professionals to enhance comfort and maintain skin hydration. This…
Sponsor: Lynch Regenerative Medicine • Aim: Symptom relief
Last updated Jul 23, 2026 00:00 UTC
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Simple pelvic floor therapy may ease radiation side effects for cervical cancer patients
Symptom relief Recruiting nowThis is a single arm phase II study in which 28 patients who will be undergoing definitive pelvic external beam radiation therapy for cervical cancer will receive pelvic floor physical therapy 4 weeks after completing radiation therapy.
Sponsor: University of Cincinnati • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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New obesity drug SA030 enters first human safety trial
Disease control Not yet recruitingThis study is the first time SA030 is being given to people. The goal is to understand how safe it is, how well it is tolerated, and how the body processes and responds to a single dose of SA030 in individuals who are overweight or obese. Over the last few decades, more and more…
Phase 1 • Sponsor: Suzhou Siran Biotechnology Co.,Ltd. • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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Thigh-Worn gadget could reveal hidden impact of FND
Knowledge-focused Recruiting nowThis study evaluates whether remotely measured daily activity behavior, captured through a thigh-worn accelerometer, can serve as a reliable and ecologically valid indicator of symptom impact in individuals with Functional Neurologic Disorder (FND). Current clinician-rated assess…
Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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Grinding your teeth? it might be connected to pelvic pain and erectile dysfunction
Knowledge-focused By invitation onlyBruxism is a parafunctional activity characterized by clenching or grinding of the teeth during wakefulness or sleep. Increasing evidence suggests that bruxism is not only related to orofacial structures but may also be associated with broader musculoskeletal and psychosocial con…
Sponsor: Akdeniz University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Portable EEG device probes delirium risk in ICU patients
Knowledge-focused Recruiting nowThe purpose of this study is to assess the prevalence of EEG abnormalities on Ceribell POC EEG in adult medical, surgical, and cardiovascular ICU patients with high risk of delirium
Sponsor: Ceribell Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Stress ball may calm nerves before kidney surgery, trial hopes
Symptom relief Recruiting nowThis study was designed as a randomized controlled trial to determine the effect of a stress ball applied before retrograde intrarenal surgery on patients' anxiety levels, surgical fear, and hemodynamic parameters.
Sponsor: Mersin University • Aim: Symptom relief
Last updated Sep 10, 2026 00:00 UTC
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New dental implant technique uses your own bone to rebuild jaw
Disease control Not yet recruitingCGF membranes will be prepared using a swing-lock centrifuge. A full-thickness mucoperiosteal flap will be elevated in a narrow alveolar ridge. Implants will be inserted. Autologous bone chips will be harvested via bone scraping and used for augmentation, CGF membranes will be pl…
Sponsor: Cairo University • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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New tool may predict who will suffer after achilles surgery
Knowledge-focused CompletedThis is a single-center retrospective cohort study to identify independent risk factors and develop a predictive nomogram for moderate-to-severe pain within 24 hours after Achilles tendon surgery.
Sponsor: Min Li • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Smartwatch nudges aim to get AF patients moving more
Symptom relief Recruiting nowThis project aims to bridge the gap between technology and healthcare by developing a biofeedback intervention that enables daily monitoring of atrial fibrillation episodes and physical activity levels. The main question it aims to answer is: Is a co-designed, usability-tested, …
Sponsor: Liverpool John Moores University • Aim: Symptom relief
Last updated Jun 27, 2026 12:36 UTC
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Phone support eases pregnancy anxiety, study finds
Symptom relief Recruiting nowThe goal of this clinical trial is to compare the effects of tele-nursing-supported Mindfetalness method versus Mindfetalness alone method on maternal anxiety and prenatal attachment in pregnant women. The main questions it aims to answer are: * H1: Tele-nursing-supported Mindfe…
Sponsor: Abant Izzet Baysal University • Aim: Symptom relief
Last updated Aug 08, 2026 00:03 UTC
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New acid blocker may beat standard treatment for stomach bug
Disease control Recruiting nowThe goal of this clinical trial is to compare the efficacy and safety of vonoprazan-based levofloxacin-containing triple therapy with esomeprazole-based levofloxacin-containing triple therapy for eradication of Helicobacter pylori infection in adults with dyspepsia. The main que…
Phase 4 • Sponsor: Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Can a squirt of medicine in the windpipe stop coughing after sinus surgery?
Symptom relief Not yet recruitingcompare the efficacy of intratracheal dexmedetomidine versus intratracheal lidocaine in achieving smooth tracheal extubation in patients undergoing Functional Endoscopic Sinus surgery and reconstructive nasal surgeries under general anesthesia.
Phase 4 • Sponsor: Younes Ahmed Younes • Aim: Symptom relief
Last updated Jun 27, 2026 12:02 UTC