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Can a squirt of medicine in the windpipe stop coughing after sinus surgery?

NCT ID NCT07504497

Symptom relief Sponsor: Younes Ahmed Younes Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two drugs, dexmedetomidine and lidocaine, sprayed into the windpipe to see which one reduces coughing better when patients wake up from sinus or nose surgery. 120 adults having elective sinus surgery will take part. The goal is a smoother, more comfortable recovery from anesthesia.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
dexmedetomidine
What this could lead to
If it works, this could offer a simple way to reduce coughing and discomfort when waking up from sinus surgery.
What could go wrong
This is a small, early-phase study (120 people) comparing two drugs; results may not apply to other surgeries or patients with lung problems.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

About 120 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Apr 2026

An estimate. Start dates often move.

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * \- Age 18-60 years. * Elective FESS under general anesthesia. * ASA Physical Status I-II Exclusion Criteria: * Allergy to dexmedetomidine or lidocaine * Anticipated difficult airway * Chronic pulmonary diseases (asthma, COPD) * Uncontrolled hypertension or ischemic heart disease * Patient refusal

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Fess operation

How to take part

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  1. The official record

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    Open the record ↗

  2. A doctor treating you

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