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116076 trials found · Page 3187 of 5804
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New combo sedation aims to calm recovery agitation
Symptom relief CompletedUsing Ketamine for procedural sedation in adults is often uncomfortable for emergency physicians because of the significant proportion of patients experimenting recovery agitation. The investigators believe that combining propofol to ketamine, the proportion of recovery agitation…
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Symptom relief
Last updated Jun 27, 2026 12:01 UTC
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Could sharing your HIV status help you stick to medication?
Knowledge-focused CompletedThe investigators believe that disclosure of HIV status could influence medication adherence. If disclosure leads to social support, adherence could be improved. This study purpose is to assess correlation between disclosure and medication adherence, and to describe people whose …
Sponsor: Center for Primary Care and Public Health (Unisante), University of Lausanne, Switzerland • Aim: Knowledge-focused
Last updated Jul 19, 2026 00:00 UTC
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New oral drug combo shows promise in early cancer trial
Disease control CompletedBackground: \- FdCyd (also called 5-fluoro-2'-deoxycytidine) and THU (also called tetrahydrouridine) are experimental cancer treatment drugs. FdCyd may change how genes work in cancer cells. THU helps keep FdCyd from being broken down by the body. FdCyd and THU have been given t…
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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New program aims to prevent second fractures in older women
Prevention CompletedOsteoporosis is a disease characterized by reduced bone mass and increased skeletal fragility, predisposing to an increased fracture risk. The presence of a low trauma fracture is a powerful predictor of future fractures and about 50% of patients with a fragility fracture will su…
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Prevention
Last updated Jun 27, 2026 08:05 UTC
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New scan spots hidden oxygen shortage in pancreatic tumors
Diagnosis CompletedThis is a diagnostic study to look for low levels of oxygen (hypoxia) in pancreatic cancer using an imaging test called positron emission tomography (PET). Hypoxia can influence how pancreatic cancer grows and responds to treatments such as chemotherapy and radiotherapy. The use …
Sponsor: University Health Network, Toronto • Aim: Diagnosis
Last updated Jun 27, 2026 13:07 UTC
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Proton therapy data collection aims to improve head and neck cancer care
Knowledge-focused OngoingThis trial collects medical information from patients with head and neck cancer that have received or are scheduled to receive proton therapy. Collecting and analyzing medical information from patients may provide information on the outcomes and treatment related side effects of …
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Zapping buttock muscles may improve sitting for spinal injury patients
Symptom relief CompletedThe aim of the study is to investigate whether there is an effect of electrical stimulation on the denervated gluteus muscle (buttocks) in individuals with chronic spinal cord injury. The expected outcome is an increase in muscle volume and a better pressure distribution during s…
Phase: NA • Sponsor: Swiss Paraplegic Research, Nottwil • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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700 patients reviewed: are minimally invasive tumor removals effective Long-Term?
Knowledge-focused CompletedThis study aims to comprehensively assess how well endoscopic treatments work for gastrointestinal submucosal tumors (SMTs)-both in the short term right after treatment and over the long run-and to figure out what factors might affect the treatment's success. Specifically, it see…
Sponsor: Xijing Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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New diabetes drug tested in kidney patients: hope or hype?
Disease control CompletedThe purpose of this study is to evaluate the PK/PD and safety of TA-7284 in patients with type 2 diabetes mellitus who have moderate renal impairment.
Phase: PHASE1 • Sponsor: Tanabe Pharma Corporation • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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New ultrasound technique could ease carpal tunnel pain without major surgery
Symptom relief CompletedThe objective of the study is to evaluate in patients suffering from carpal tunnel syndrome resistant to medical treatment, clinical course after percutaneous treatment under ultrasound guidance. 40 patients will be included in the study. The following parameters will be evaluate…
Phase: PHASE2 • Sponsor: University Hospital, Caen • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
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New tool helps parents of diabetic tots tame blood sugar
Disease control CompletedDIAB-EDUC tests in a group of young diabetic patients (less than 6 years old) a specific educational tool in order to assess its impact on glycemic control, quality of life, knowledge about the disease and its daily management, over a period of 2 years. The investigators plan to …
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
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MRI heart scan may forecast future for heart muscle disease patients
Knowledge-focused Completed: Fibrosis, in general, is a scarring process, which is characterized by fibroblast accumulation and excess deposition of extracellular matrix (ECM) proteins, which leads to distorted organ architecture and function. The contribution of fibrogenesis to impaired cardiac function i…
Phase: NA • Sponsor: Assistance Publique Hopitaux De Marseille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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New drug combo shows promise for Hard-to-Treat cancers
Disease control OngoingThis phase I trial studies the side effects and the best dose of veliparib and dinaciclib in treating patients with solid tumors that have spread to other places in the body and usually cannot be cured or controlled with treatment. Veliparib and dinaciclib may stop the growth of …
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC
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Can vitamin d tweak breast cancer genes? weight may matter
Disease control TerminatedThis is a research study of the effect of Vitamin D on breast cancer. We hope to learn whether Vitamin D can change characteristics of certain genes in a breast cancer tumor that affect its growth. We believe some of these characteristics may be influenced by body weight.
Phase: PHASE2 • Sponsor: Melinda Telli • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Heart MRI may reveal who really needs a shock device
Knowledge-focused CompletedDelayed enhanced MRI in patients (of either ischemic or non-ischemic cause) being referred for primary prevention ICD
Sponsor: Ottawa Heart Institute Research Corporation • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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Breathing exercise boosts rehab for COPD patients
Symptom relief CompletedThe purpose of this study is to determinate whether inspiratory muscle training (IMT) associated with a conventional respiratory rehabilitation program is more effective than a conventional respiratory rehabilitation program alone,on Dyspnea in chronic obstructive pulmonary disea…
Phase: NA • Sponsor: University Hospital, Brest • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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Job support program shows promise for mental health recovery
Knowledge-focused CompletedThe aim of the present study, is to evaluate the effect of a supported employment intervention, IPS-modified for people with mood and anxiety (IPS-MA) on employment or education, when offered to people with onset mood or anxiety disorders who are not likely to be able to return t…
Phase: NA • Sponsor: Amager Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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Hearing loss pill shows promise in early trial
Prevention CompletedExposure to loud sounds can cause hearing loss. The purpose of this research study is to evaluate potential prevention of temporary changes in hearing that may occur after listening to music through an iPod or personal music player. We will measure temporary changes in hearing in…
Phase: PHASE2 • Sponsor: Sound Pharmaceuticals, Incorporated • Aim: Prevention
Last updated Jun 27, 2026 13:00 UTC
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Brain zaps curb smoking cravings in hardcore nicotine addicts
Symptom relief CompletedThe fight against smoking is a public health priority. Without help, fewer than 5% of des smokers are abstinent at 12 months after smoking cessation. Despite well-managed attempts at smoking cessation with nicotine substitutes, the rate of success at 12 months in patients depend…
Phase: NA • Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Symptom relief
Last updated Jun 27, 2026 09:02 UTC
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Can a short workout before breast cancer surgery change tumor markers?
Knowledge-focused OngoingThis study is designed to look at the changes that occur in women who take part in exercise and Mind-Body programs between breast cancer diagnosis and breast surgery. The investigators will look at changes in stress, anxiety, mood and quality of life, to see if these types of sho…
Phase: NA • Sponsor: Dana-Farber Cancer Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC