Syfovre safety check: Real-World study tracks eye drug in 300 patients

NCT ID NCT06161584

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looks at how safe and tolerable the drug pegcetacoplan (Syfovre) is for people with geographic atrophy, a form of advanced age-related macular degeneration that causes vision loss. About 300 patients who are already prescribed the drug by their doctor will be followed to track side effects and how the drug is used in real life. The goal is to understand treatment patterns and safety outside of a controlled clinical trial.

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Conditions

The condition(s) this trial relates to.

age-related macular degeneration dry age related macular degeneration Geographic Atrophy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Bay Area Retina Associates (01-005)

    Walnut Creek, California, 94598, United States

  • Black Hills Regional Eye Institute (01-010)

    Rapid City, South Dakota, 57701, United States

  • California Retina Consultants (01-026)

    Bakersfield, California, 93309, United States

  • California Retina Consultants (01-027)

    Santa Barbara, California, 93103, United States

  • Colorado Retina Associates, PLLC (01-011)

    Lakewood, Colorado, 80228, United States

  • Cumberland Valley Retina Consultants, P.C. (01-002)

    Hagerstown, Maryland, 21740, United States

  • Georgia Retina (01-032)

    Marietta, Georgia, 30060, United States

  • Illinois Retina Associates (01-035)

    Fullerton, California, 92835, United States

  • Illinois Retina Associates (01-037)

    Oak Park, Illinois, 60304, United States

  • Integrated Clinical Research (01-024)

    Abilene, Texas, 79606, United States

  • Long Island Vitreoretinal Consultants (01-013)

    Westbury, New York, 11590, United States

  • Mid Atlantic Retina (01-001)

    Bethlehem, Pennsylvania, 18017, United States

  • Mid Atlantic Retina (01-031)

    Cherry Hill, New Jersey, 08906, United States

  • Mid Atlantic Retina Research (01-014)

    Cherry Hill, New Jersey, 08034, United States

  • Mid Atlantic Retina Specialist (01-029)

    Hagerstown, Maryland, 21740, United States

  • OCLI Research Department (01-007)

    Oceanside, New York, 11572, United States

  • Pacific Northwest Retina (01-036)

    Bellevue, Washington, 98004, United States

  • Retina Associates of Cleveland, Inc. (01-016)

    Youngstown, Ohio, 44505, United States

  • Retina Associates of Cleveland, Inc. (01-017)

    Cleveland, Ohio, 44122, United States

  • Retina Associates of Cleveland, Inc. (01-022)

    Cleveland, Ohio, 44130, United States

  • Retina Consultants San Diego Inc. (01-018)

    Poway, California, 92064, United States

  • Retina Consultants of Minnesota, PLLC (01-025)

    Edina, Minnesota, 55435, United States

  • Retina Consultants of Texas (01-003)

    The Woodlands, Texas, 77384, United States

  • Retina Consultants of Texas (01-004)

    Bellaire, Texas, 77401, United States

  • Retina Specialty Institute (01-019)

    Pensacola, Florida, 32503, United States

  • Retina-Vitreous Associates Medical Group (01-020)

    Beverly Hills, California, 90211, United States

  • Retinal Consultants Medical Group Inc (01-008)

    Modesto, California, 95356, United States

  • South East Retina Center, PC (01-030)

    Augusta, Georgia, 30909, United States

  • Tennessee Retina (01-033)

    Nashville, Tennessee, 37203, United States

  • Texas Retina Associates (01-028)

    Dallas, Texas, 75231, United States

  • The Retina Care Center (01-023)

    Baltimore, Maryland, 21209, United States

  • The Retina Care Center (01-034) - Satellite Site

    York, Pennsylvania, 17402, United States

  • The Retina Group of Washington (01-021)

    Fairfax, Virginia, 22031, United States

  • Western Carolina Retinal Associates, PA (01-009)

    Asheville, North Carolina, 28803, United States