Real-World study tracks Apalutamide's impact on prostate cancer patients

NCT ID NCT06019676

First seen Nov 01, 2025 · Last updated May 03, 2026 · Updated 26 times

Summary

This study follows 170 men with metastatic hormone-sensitive prostate cancer who choose to take apalutamide as part of their standard care. Researchers will measure how well the drug lowers PSA levels and how it affects fatigue, thinking skills, and overall quality of life using questionnaires over two years. The goal is to see if results from controlled trials hold true in real-world settings.

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Contacts and locations

Locations

  • Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust

    Cambridge, CB2 0QQ, United Kingdom

  • Buckinghamshire Healthcare NHS Trust

    Aylesbury, HP21 8AL, United Kingdom

  • Clatterbrdige Cancer Centre, NHS Foundation Trust

    Liverpool, CH63 4JY, United Kingdom

  • East Lancashire Hospitals NHS Trust

    Blackburn, BB2 3HH, United Kingdom

  • Freeman Hospital, The Newcastle upon Tyne Hospitals NHS Foundation Trust

    Newcastle, NE7 7DN, United Kingdom

  • Northern Ireland Cancer Centre, Belfast Health & Social Care Trust

    Belfast, BT9 7AB, United Kingdom

  • South Tyneside and Sunderland NHS Foundation Trust

    Newcastle, NE34 0PL, United Kingdom

  • The James Cook University Hospital, South Tees Hospitals NHS Foundation Trust

    Middlesbrough, TS4 3BW, United Kingdom

  • The Royal Marsden Hospital

    Sutton, Surrey, SM2 5PT, United Kingdom

  • The University Hospital of North Tees

    Stockton-on-Tees, TS19 8PE, United Kingdom

  • University Hospitals of Morecambe Bay NHS Foundation Trust

    Lancaster, LA1 4RP, United Kingdom

  • Velindre Cancer Centre, Velindre University NHS Trust

    Cardiff, CF14 2TL, United Kingdom

Conditions

Explore the condition pages connected to this study.