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127005 trials found · Page 2310 of 6351
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Could a simple tool and exercise ease knee arthritis pain without drugs?
Symptom relief CompletedTo determine the efficacy of IASTM as an adjunct to therapeutic exercises on pain, range of motion, and functional performance in individuals with knee OA.
Sponsor: Foundation of Medical Research and Laboratories, Pakistan • Aim: Symptom relief
Last updated Jul 19, 2026 00:00 UTC
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New study seeks best way to remove stomach tumors without major surgery
Disease control Recruiting nowEndoscopic resection has been increasing utilized as the treatment for small size gastrointestinal stromal tumors (GIST), of which the best resection method has not been identified. We aim to compare the outcomes of endoscopic full thickness resection (EFTR) versus submucosal tun…
Sponsor: Chinese University of Hong Kong • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
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Could a gentle zap protect older hearts from hidden lung threat after surgery?
Disease control Stopped earlyObjective To investigate the safety and effectiveness of interference electrical stimulation in the prevention of silent aspiration after heart valve surgery in elderly patients. Silent aspiration was diagnosed when either pepsin level \>200 ng/ml or α-amylase level \>1685 U/L wa…
Sponsor: Fujian Medical University Union Hospital • Aim: Disease control
Last updated Jul 19, 2026 00:00 UTC
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New breathing technique could uncover hidden stroke cause
Diagnosis Recruiting nowIschemic stroke represents a major public health issue, leading to significant disabilities and deaths worldwide. When no clear cause for stroke is found following a comprehensive cardiovascular evaluation (no atrial fibrillation, cardiac masses, or atherosclerosis) i.e. cryptoge…
Sponsor: Ottawa Heart Institute Research Corporation • Aim: Diagnosis
Last updated Jun 27, 2026 12:26 UTC
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Could an antidepressant tame hot flashes without hormones?
Symptom relief Completedevaluate the efficacy of paroxetine in the management of vasomotor symptoms in patients with surgical menopause, in order to seek an alternative therapy to hormone therapy, which is associated with proinflammatory and procoagulant effects that increase the risk of thrombosis and …
Phase 2 • Sponsor: Universidad Nacional Autonoma de Honduras • Aim: Symptom relief
Last updated Jun 26, 2026 18:20 UTC
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Laughter yoga: a surprising way to help cancer patients feel better?
Symptom relief CompletedNon-pharmacological interventions that promote positive emotional states and coping may play a critical role in care of cancer patients undergoing chemotherapy.This study aimed to evaluate the effects of laughter yoga on symptoms, hope, and life engagement levels in cancer patien…
Sponsor: Ataturk University • Aim: Symptom relief
Last updated Aug 28, 2026 00:00 UTC
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Hidden toll of routine ICU procedure revealed: suctioning may spike pain and stress
Knowledge-focused Recruiting nowThe goal of this experimental study is to understand if endotracheal tube (ETT) suctioning increases pain and causes stress on the body in intubated adult ICU patients. These patients are already on ventilators, which means they need suctioning to keep their airways clear, but th…
Sponsor: Loma Linda University • Aim: Knowledge-focused
Last updated Jul 12, 2026 00:00 UTC
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Could cialis go over the counter? new study tests safe access without a prescription
Disease control CompletedThe purpose of this actual use trial (AUT) is to evaluate if participants can appropriately select and use the study product \[Cialis over the counter (OTC)\] using the labeling and the mandatory health survey assessment (HSA) for duration of 4-months.
Phase 3 • Sponsor: Sanofi • Aim: Disease control
Last updated Jul 15, 2026 00:00 UTC
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New psoriasis drug tracked in everyday patients
Disease control Recruiting nowThe purpose of this study is to assess the real-world effectiveness of deucravacitinib treatment in adults diagnosed with moderate-to-severe plaque psoriasis
Sponsor: Bristol-Myers Squibb • Aim: Disease control
Last updated Jun 27, 2026 12:34 UTC
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New MRI scanner could spot ACL tears without surgery
Diagnosis Recruiting nowThis study will be conducted to see if a new Magnetic Resonance Imaging (MRI) scanner could give additional information or help view the body in a different way. The new scanner may be useful to diagnose conditions affecting tissues such as ligaments, tendons and cartilage more a…
Sponsor: Imperial College London • Aim: Diagnosis
Last updated Jun 27, 2026 08:14 UTC
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New drug aims to tame dangerous blood fats in heart patients
Disease control Recruiting nowThe goal of this clinical trial is to learn if drug RBD5044 works to treat mixed dyslipidemia in adults. It will also learn about the safety of drug RBD5044. The main questions it aims to answer are: Does drug RBD5044 reduce the triglyceride levels? What medical problems may par…
Phase 2 • Sponsor: Ribocure Pharmaceuticals AB • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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New hope for heart inflammation sufferers: experimental drug VTX2735 enters Mid-Stage trial
Disease control Recruiting nowThis is a study to understand if taking VTX2735 is safe and effective in participants diagnosed with Recurrent Pericarditis (RP). Cohort A will include approximately 10 participants and will consist of the following: * A 30-day Screening Period (to see if a participant qualifie…
Phase 2 • Sponsor: Zomagen Biosciences Ltd. • Aim: Disease control
Last updated Sep 10, 2026 01:00 UTC
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New HIV drug could offer safer alternative for First-Time patients
Disease control Recruiting nowPhase III trial evaluating doravirine as an alternative to dolutegravir in treatment naïve people living with HIV-1 infection.
Phase 3 • Sponsor: ANRS, Emerging Infectious Diseases • Aim: Disease control
Last updated Jul 29, 2026 00:00 UTC
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Lab-Grown 'Mini Tumors' could personalize pancreatic cancer care
Knowledge-focused Recruiting nowPancreatic ductal adenocarcinoma (PDAC) has the poorest prognosis of all digestive cancers due to lack of early diagnosis and limited response to treatment. Patient-derived organoid technology has become a mainstay of precision oncology, enabling personalised functional character…
Sponsor: IHU Strasbourg • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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New study aims to catch lung cancer early in french smokers
Knowledge-focused Recruiting nowThe aim of this study is to evaluate the feasibility of performing a first screening for bronchopulmonary cancer by thoracic scanner in a French cohort within a dedicated, effective and structured network in the pilot centers participating in the study.
Sponsor: Institut Curie • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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New tissue graft shows promise for breast reconstruction after mastectomy
Disease control OngoingThis retrospective, single-site study will provide information regarding the efficiency of AlloMend® Acellular Dermal Matrix allograft in Pre-Pectoral Breast Reconstruction surgery following a single or double mastectomy.
Sponsor: AlloSource • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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Pumping iron for a stronger heart: can resistance training reverse muscle loss in seniors?
Symptom relief CompletedThe goal of study is to evaluate the effects of an eight-week machine-based resistance training program on managing sarcopenia in older outpatients with chronic heart failure (HF) at Military Hospital 175.
Sponsor: Kieu Dang Phuong Nguyen • Aim: Symptom relief
Last updated Aug 08, 2026 00:03 UTC
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Gum disease gel: could spermidine make deep cleaning more effective?
Disease control CompletedThis study investigates the effectiveness of using a spermidine-based gel as an adjunct to minimally invasive non-surgical periodontal therapy (MINST) for treating periodontitis. The primary outcome is to assess whether the addition of spermidine gel reduces pocket depth (PPD) co…
Phase 4 • Sponsor: Luca Ramaglia • Aim: Disease control
Last updated Jul 17, 2026 00:00 UTC
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New hip device aims to delay full replacement
Disease control OngoingThe goal of this clinical trial is to evaluate the safety and effectiveness of the Polymotion Hip Resurfacing (PHR) System compared to total hip arthroplasty, for adults who require hip resurfacing arthroplasty due to 1) non-inflammatory arthritis (degenerative joint disease) suc…
Sponsor: JointMedica Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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One-Size-Fits-All diet fails? mayo clinic tests custom Weight-Loss plans
Disease control Recruiting nowThe purpose of this study is to develop an evidence-based precision medicine approach for obesity that enhances weight loss and promotes weight loss maintenance.
Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 27, 2026 13:05 UTC