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New HIV drug could offer safer alternative for First-Time patients

NCT ID NCT06203132

Recruiting now Disease control Sponsor: ANRS, Emerging Infectious Diseases Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 28, 2026 · Updated 2 times

Summary

This study compares two HIV medications, doravirine and dolutegravir, in people who have never taken HIV treatment before. About 610 adults with HIV-1 will receive one of these drugs along with standard medicines. The goal is to see if doravirine works just as well as dolutegravir at controlling the virus after 48 weeks, while possibly causing fewer side effects like weight gain.

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Conditions

The condition(s) this trial relates to.

HIV infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIV-1-INFECTION

Contacts and locations

Locations

  • AP-HP Bichat Claude Bernard - Service des Maladies Infectieuses et Tropicales

    RECRUITING

    Paris, 75018, France

  • AP-HP Hôpital Lariboisière - Service de Maladies Infectieuses et Tropicales

    RECRUITING

    Paris, 75010, France

  • AP-HP Hôpital Pitié Salpêtrière - Service des Maladies Infectieuses et Tropicales

    RECRUITING

    Paris, 75013, France

  • AP-HP Hôpital Saint Antoine - Service des Maladies Infectieuses et Tropicales

    RECRUITING

    Paris, 75012, France

  • AP-HP Hôpital Saint Louis - Service des Maladies Infectieuses et Tropicales

    RECRUITING

    Paris, 75010, France

  • CHU Bordeaux Pellegrin - Service des Maladies Infectieuses et Tropicales

    RECRUITING

    Bordeaux, 33075, France

  • CHU Bordeaux St André - Service de Médecine Interne

    RECRUITING

    Bordeaux, 33075, France

  • CHU Montpellier - Hôpital La Colombière - Service des Maladies Infectieuses et Tropicales

    RECRUITING

    Montpellier, 34295, France

  • CHU Nantes Hôtel Dieu - Service des Maladies infectieuses et tropicales

    RECRUITING

    Nantes, 44093, France

  • CHU de Treichville, Service des Maladies Infectieuses et Tropicales (SMIT)

    RECRUITING

    Abidjan, Côte d’Ivoire

  • Centre Médical de Suivi des Donneurs de Sang (CMSDS) - Centre National de Transfusion Sanguine (CNTS)

    NOT_YET_RECRUITING

    Abidjan, Côte d’Ivoire

  • Centre de prise en charge de Recherche et de Formation (CEPREF)

    RECRUITING

    Abidjan, Côte d’Ivoire

  • Centro de Saúde 1o de Maio

    RECRUITING

    Maputo, Mozambique

  • Chiangrai Prachanukroh

    RECRUITING

    Chiang Rai, 57000, Thailand

  • Hospital Geral de Nova Iguaçu

    RECRUITING

    Nova Iguaçu, Rio de Janeiro, 26030-380, Brazil

  • Hôpital Central de Yaoundé

    RECRUITING

    Yaoundé, Cameroon

  • Laboratory on Clinical research on AIDS-INI FIOCRUZ

    RECRUITING

    Rio de Janeiro, Rio de Janeiro, 21040-900, Brazil

  • Lampang Hospital Internal Medicine department

    RECRUITING

    Lampang, 52000, Thailand

  • Phayao Hospital Internal Medicine department

    RECRUITING

    Phayao, 56000, Thailand

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