Could a common antidepressant tame hot flashes after surgery?

NCT ID NCT06763484

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 26 times

Summary

This study tested whether paroxetine, a medication usually used for depression, can reduce hot flashes and night sweats in women who entered menopause after having their ovaries removed. 90 women took either paroxetine or a placebo for 6 months. Researchers measured changes in menopause symptoms and tracked side effects. The goal was to find a safer alternative to hormone therapy, which can raise the risk of blood clots.

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Contacts and locations

Locations

  • Instituto Hondureño de Seguridad Social

    Tegucigalpa, Francisco Morazán Department, 11101, Honduras

Conditions

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