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Could a simple tool and exercise ease knee arthritis pain without drugs?

NCT ID NCT07710209

Symptom relief Sponsor: Foundation of Medical Research and Laboratories, Pakistan Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 17, 2026 · Last updated Jul 17, 2026

Summary

This study tests whether adding instrument-assisted soft tissue mobilization (IASTM) to standard therapeutic exercises can better reduce pain, improve knee range of motion, and boost daily function in people with knee osteoarthritis. Fifty adults aged 40 to 60 with knee OA will receive either IASTM plus exercises or exercises alone for six weeks. Researchers will measure changes in pain, motion, and function at the start and end of treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
instrument-assisted soft tissue mobilization (IASTM) plus therapeutic exercise
What this could lead to
If effective, this combination approach could offer a non-drug way to reduce pain and improve mobility in people with knee osteoarthritis.
What could go wrong
This is a small, early-stage trial with only 50 participants, so results may not apply broadly. The treatment is also time-intensive and requires a trained therapist.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

50 people

The number who actually took part.

Started

Feb 2025

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Osteoarthritis, both gender, Age between 40-60 years. - Exclusion Criteria: Not meeting the inclusion criteria, underwent recent surgery of lower limb. \-

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Knee osteoarthritis (OA)

Contacts and locations

Locations

  • FMRL

    Karachi, Sindh, Pakistan

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