KNEE OSTEOARTHRITIS (OA)
Clinical trials for KNEE OSTEOARTHRITIS (OA) explained in plain language.
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New weekly shot aims to melt weight and soothe aching knees
Symptom relief Recruiting nowThis Phase 3 trial tests whether a once-weekly injection called NNC0487-0111 can help people with overweight or obesity and knee osteoarthritis lose weight and feel less pain. About 400 adults will receive either the drug or a placebo for several weeks. Researchers will measure c…
Matched conditions: KNEE OSTEOARTHRITIS (OA)
Phase: PHASE3 • Sponsor: Novo Nordisk A/S • Aim: Symptom relief
Last updated Jul 11, 2026 00:00 UTC
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Knee pain relief: study tests if ibuprofen ruins injection benefits
Symptom relief Recruiting nowThis study looks at whether taking ibuprofen (a common painkiller) along with dextrose prolotherapy injections affects pain and function in people with knee osteoarthritis. Researchers will give 68 adults either ibuprofen or a placebo for 7 days after each of three injections. Th…
Matched conditions: KNEE OSTEOARTHRITIS (OA)
Phase: PHASE2 • Sponsor: David Grant U.S. Air Force Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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New imaging study to uncover why knee realignment works for some OA patients
Knowledge-focused Recruiting nowThis study will use advanced CT and MRI scans to see how knee realignment treatments (surgery or braces) affect bone structure and cartilage in 30 people with early knee osteoarthritis. Researchers want to understand why some treatments fail, so they can improve care for younger …
Matched conditions: KNEE OSTEOARTHRITIS (OA)
Phase: NA • Sponsor: Universitaire Ziekenhuizen KU Leuven • Aim: Knowledge-focused
Last updated Jul 12, 2026 00:00 UTC
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New registry aims to see if blocking knee arteries eases arthritis pain
Knowledge-focused Recruiting nowThis study is creating a registry to track how well a procedure called genicular artery embolization (GAE) works for knee osteoarthritis pain over time. Up to 100 adults with mild to moderate knee arthritis that hasn't improved with standard treatments will be enrolled. The goal …
Matched conditions: KNEE OSTEOARTHRITIS (OA)
Sponsor: University of Chicago • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
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Scientists investigate why knee pain varies so much between patients
Knowledge-focused Recruiting nowThis observational study looks at why some people with knee osteoarthritis have worse pain than others, even when their knee damage looks similar on X-rays. Researchers will study 300 adults aged 45-80 with chronic knee pain. Participants will complete surveys, physical tests, kn…
Matched conditions: KNEE OSTEOARTHRITIS (OA)
Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC