New registry aims to see if blocking knee arteries eases arthritis pain

NCT ID NCT06781463

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is creating a registry to track how well a procedure called genicular artery embolization (GAE) works for knee osteoarthritis pain over time. Up to 100 adults with mild to moderate knee arthritis that hasn't improved with standard treatments will be enrolled. The goal is to measure pain changes and any side effects, comparing GAE to a sham procedure at 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this registry could provide evidence that genicular artery embolization is a safe and effective option for knee osteoarthritis pain, potentially offering an alternative to surgery.

What could go wrong

This is an observational registry, not a controlled trial, so results may be less definitive. The procedure carries risks like bleeding or infection, and the study is small (100 patients), so findings may not apply to everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Chicago Duchossois Center for Advanced Medicine

    RECRUITING

    Chicago, Illinois, 60637, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact