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Smart immune cells take aim at Hard-to-Treat cancers

NCT ID NCT06051695

First seen Dec 12, 2025 · Last updated Jun 10, 2026 · Updated 27 times

Summary

This study tests a new treatment using a patient's own immune cells, called CAR T cells, that are specially designed to target and kill solid tumor cells while leaving healthy cells unharmed. It is for adults with certain advanced cancers, including lung, colon, pancreatic, ovarian, and mesothelioma, that have not responded to other treatments. The study has two phases: first to find a safe dose, and second to see if the treatment shrinks tumors.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Banner Health

    RECRUITING

    Gilbert, Arizona, 85234, United States

    Contact

    Contact Email: •••••@•••••

  • Fred Hutchinson Cancer Center

    RECRUITING

    Seattle, Washington, 98109, United States

    Contact Email: •••••@•••••

    Contact

    Contact

  • Mayo Clinic

    RECRUITING

    Jacksonville, Florida, 32224, United States

    Contact Email: •••••@•••••

    Contact

  • Mayo Clinic Rochester

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact

    Contact Email: •••••@•••••

  • Moffitt Cancer Center

    RECRUITING

    Tampa, Florida, 33606, United States

    Contact

    Contact Email: •••••@•••••

  • NYU Langone Medical Center

    RECRUITING

    New York, New York, 10016, United States

    Contact Email: •••••@•••••

    Contact

  • Stanford University

    RECRUITING

    Stanford, California, 94305, United States

    Contact Email: •••••@•••••

    Contact

  • The Ohio State University Comprehensive Cancer Center

    RECRUITING

    Columbus, Ohio, 43210, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • UCLA Medical Center

    RECRUITING

    Los Angeles, California, 90404, United States

    Contact

    Contact Email: •••••@•••••

  • UCSD Moores Cancer Center

    RECRUITING

    La Jolla, California, 92093, United States

    Contact Email: •••••@•••••

    Contact

  • Vanderbilt University Medical Center

    RECRUITING

    Nashville, Tennessee, 37232, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Washington University

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact Email: •••••@•••••

    Contact

    Contact

Conditions

The condition(s) this trial relates to.

colonic neoplasm colorectal neoplasm lung neoplasm mesothelioma Mesothelioma, Malignant neoplasm non-small cell lung carcinoma ovarian cancer pancreatic neoplasm rectal neoplasm Recurrence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.