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Can AI make lung cancer scans easier to read?
NCT ID NCT07829640
First seen Sep 21, 2026 · Last updated Sep 21, 2026
Summary
Researchers are building an artificial intelligence system that analyzes chest CT images and offers decision support to doctors reading those scans for lung cancer. They use deidentified CT exams from routine care to develop and lock the AI models. In the prospective stage, about 12 to 15 physicians each complete two reading sessions in random order: one without AI help and one with AI help, separated by at least four weeks. The study compares diagnostic accuracy, reading time, confidence, and agreement between readers. All readings happen offline, and the AI is not used for actual patient care.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- an artificial intelligence decision-support system that analyzes chest CT images
- What this could lead to
- If it works, this could point toward AI-assisted chest CT reading that helps doctors spot lung cancer more accurately and possibly faster.
- What could go wrong
- This is a small, single-center reader study with 12 to 15 physicians, and the AI is tested offline, not in real patient care. The AI may not improve accuracy, and incorrect AI suggestions could mislead readers.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 15 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Aug 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Physicians with education or training relevant to medical imaging * Experience in interpreting chest CT examinations * Ability to complete the required study training and both reading sessions * Willingness to provide written informed consent and comply with study procedures Exclusion Criteria: * Failure to complete the required study training * Inability or unwillingness to complete both reading sessions as required * Any protocol deviation likely to compromise the validity of the reader-study data
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, 430022, China
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