Zhejiang University

This study tests a treatment called CD19 CAR-T therapy for people newly diagnosed with a fast-growing type of large B-cell lymphoma that is hard to treat. About 40 adults will receive the therapy to see if it can make the cancer disappear completely. The goal is to improve outcom…

This early-phase study tests a new treatment called CNCT19 for people with advanced liver cancer that cannot be surgically removed or has come back after other treatments. The therapy uses a patient's own immune cells, modified to target cancer cells. The main goals are to check …

This study tests whether combining an immunotherapy drug (serplulimab) with chemotherapy (CAPEOX) and an anti-inflammatory drug (celecoxib) can shrink locally advanced rectal cancer before surgery. It includes 50 adults whose tumors are a common type that often doesn't respond we…

This early-stage study tests a new drug called KSV01 in 30 adults with a type of blood cancer (B-ALL) that has come back or not responded to standard treatments. The main goal is to check if the drug is safe and what side effects it may cause. Researchers will also look for early…

This study tests whether adding a new drug called IBI343 to standard chemotherapy can help people with advanced pancreatic cancer. About 64 adults whose cancer has spread or cannot be removed will receive either the combo or chemo alone. The goal is to see if the combination shri…

This early study tests a new treatment for advanced liver cancer that has not responded to standard therapies. It uses the patient's own immune cells, which are modified in a lab to better recognize and attack cancer cells. The main goals are to check the treatment's safety and s…

This early-stage study tests a new treatment called C-CAR031 for people with advanced liver cancer that cannot be removed by surgery. The treatment uses a patient's own immune cells, modified to better recognize and attack cancer cells. The main goals are to check safety and see …

This study tests if a newer, less extensive surgery (LISH) can work as well as the standard surgery for cancers in the right part of the colon. About 568 adults with colon cancer that hasn't spread will be randomly assigned to one of the two surgeries. The main goal is to see if …

This study tests whether combining two targeted drugs (cetuximab beta and fruquintinib) with or without immunotherapy can control advanced colorectal cancer without chemotherapy. About 70 people with a specific genetic type (RAS/BRAF wild-type) will receive the treatment as their…

This study tests whether a high-flow nasal cannula (a device that delivers warm, moist oxygen at high speeds) can reduce the risk of dangerously low oxygen levels during sedated gastrointestinal endoscopy in critically ill patients. Researchers will enroll 450 adults with serious…

This study tests whether a high-flow nasal cannula (a special oxygen delivery device) can prevent low oxygen levels during sedated endoscopy in people at high risk for obstructive sleep apnea. About 600 adults with a high STOP-Bang score (indicating sleep apnea risk) will be rand…

This study tests a new device called the COMBO Endoscopy Oropharyngeal Airway in 580 obese patients undergoing sedated gastrointestinal endoscopy. The device combines oxygen support, airway management, and monitoring to prevent low oxygen levels (hypoxia), a common risk in these …

This study reviews medical records of 1,200 patients who had a breathing tube placed during surgery to find out how often voice box injuries occur and what factors increase the risk. The goal is to help doctors reduce these injuries and improve recovery. Participants are adults w…