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Engineered immune cells take on Hard-to-Treat cancers

NCT ID NCT06937567

First seen May 29, 2026 · Last updated Jun 16, 2026 · Updated 3 times

Summary

This early-stage study tests a new treatment called UCLH80-1, which uses specially engineered immune cells (CAR-T cells) to target a protein called CDH17 found on many solid tumors. The study includes up to 36 people with advanced cancers like colorectal, stomach, pancreatic, or bile duct cancer who have run out of standard options. The main goal is to check the treatment's safety and find the right dose, while also looking at whether it can shrink tumors.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The First Affiliated Hospital Zhejiang University School of Medicine

    RECRUITING

    Hangzhou, Zhejiang, China

    Contact

Conditions

The condition(s) this trial relates to.

biliary tract cancer Biliary Tract Neoplasms colorectal cancer colorectal carcinoma colorectal neoplasm gastric cancer gastric neoplasm malignant pancreatic neoplasm Neoplasm Metastasis pancreatic adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.