Yonsei University
Clinical trials sponsored by Yonsei University, explained in plain language.
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Heart stent pushed to the limit in new safety study
Disease control OngoingThis study looks at whether a drug-coated heart stent can be expanded more than its normal size to treat tricky blockages in arteries. 30 adults with coronary artery disease will have the stent placed and then checked with a special camera to see if it stays safe and effective. T…
Sponsor: Yonsei University • Aim: Disease control
Last updated May 26, 2026 05:49 UTC
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HPV vaccine combo shows promise against head and neck cancer
Disease control OngoingThis study tests whether combining an HPV DNA vaccine with immunotherapy drugs can shrink advanced head and neck cancers caused by HPV types 16 or 18 before surgery. About 56 adults with resectable tumors will receive one of three treatment combinations. The main goal is to see i…
Phase: PHASE2 • Sponsor: Yonsei University • Aim: Disease control
Last updated May 26, 2026 05:48 UTC
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Heart stent patients: which statin combo keeps cholesterol lower longer?
Disease control OngoingThis study compares two cholesterol-lowering drug combinations (rosuvastatin/ezetimibe vs. atorvastatin/ezetimibe) in 200 adults who have received a heart stent. The goal is to see which combo better keeps LDL cholesterol below 55 mg/dL and causes fewer side effects like muscle p…
Phase: PHASE4 • Sponsor: Yonsei University • Aim: Disease control
Last updated May 26, 2026 04:38 UTC
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New hope for lung cancer patients with brain tumors: targeted drug T-DXd under study
Disease control ENROLLING_BY_INVITATIONThis phase 2 trial tests the drug T-DXd (Enhertu) in 27 adults with advanced HER2-mutant non-small cell lung cancer that has spread to the brain but is not causing symptoms. The main goal is to see how long the drug can keep brain tumors from growing. T-DXd is already approved fo…
Phase: PHASE2 • Sponsor: Yonsei University • Aim: Disease control
Last updated May 26, 2026 04:37 UTC
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New stent shows promise for tough heart blockages
Disease control OngoingThis study is testing a special drug-coated stent (Cre8) in 300 people with long blockages in their heart arteries. The goal is to see if the stent is safe and effective at keeping arteries open. Participants must be 19 or older and have a blockage at least 30 mm long.
Sponsor: Yonsei University • Aim: Disease control
Last updated May 20, 2026 11:57 UTC
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Lung cancer combo shows promise after targeted therapy fails
Disease control OngoingThis study tests whether adding chemotherapy to the targeted drug lazertinib can help people with a specific type of advanced lung cancer (EGFR-mutant non-small cell lung cancer) whose cancer stopped responding to lazertinib alone. About 87 adults will receive the combination and…
Phase: PHASE2 • Sponsor: Yonsei University • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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Lung cancer drug trial aims to unlock immune secrets before surgery
Knowledge-focused OngoingThis study is for people with early-stage lung cancer that can be removed with surgery. Participants receive the immunotherapy drug durvalumab before their operation. The main goal is to see how the drug changes the tumor and immune system, not to cure the disease. About 25 peopl…
Phase: PHASE2 • Sponsor: Yonsei University • Aim: Knowledge-focused
Last updated May 26, 2026 05:58 UTC
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Smart socks and wrist trackers: the future of stroke rehab?
Knowledge-focused OngoingThis study tests whether using wearable devices and a smartphone app can help stroke survivors improve their walking and daily activity during a 6-week home exercise program. About 120 adults who can walk but have some disability will be split into two groups: one uses the wearab…
Phase: NA • Sponsor: Yonsei University • Aim: Knowledge-focused
Last updated May 26, 2026 05:55 UTC
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Scientists hunt for clues to predict who benefits from head and neck cancer immunotherapy
Knowledge-focused OngoingThis study aims to find immune-related markers in blood and tumor tissue that can predict how well patients with recurrent or metastatic head and neck cancer respond to the drug nivolumab. Researchers will analyze samples from 50 adults who have already tried platinum chemotherap…
Phase: NA • Sponsor: Yonsei University • Aim: Knowledge-focused
Last updated May 26, 2026 05:43 UTC
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Wrist artery study aims to improve heart procedure safety
Knowledge-focused OngoingThis study is a registry that will track 3600 adults who need heart artery exams or treatments. Researchers want to see how well and how safely doctors can use a small wrist artery (the distal radial artery) for these procedures. The goal is to gather information, not to test a n…
Sponsor: Yonsei University • Aim: Knowledge-focused
Last updated May 26, 2026 04:38 UTC
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Massive korean study tests diabetes drug after heart attacks
Knowledge-focused OngoingThis study looks at whether a common diabetes drug (SGLT2 inhibitor) can help prevent another heart attack or stroke in people with type 2 diabetes who have already had a heart attack. Researchers will compare the health outcomes of 200,000 patients who took either an SGLT2 inhib…
Sponsor: Yonsei University • Aim: Knowledge-focused
Last updated May 22, 2026 13:52 UTC