Vanderbilt University
Clinical trials sponsored by Vanderbilt University, explained in plain language.
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Teaching joy: new program targets anhedonia in kids of depressed moms
Prevention CompletedThis study tested whether an 8-week program focused on boosting positive emotions could improve how children of mothers with depression process rewards. 73 children aged 8-12 and their mothers participated. The program used cognitive and behavioral skills to up-regulate positive …
Phase: NA • Sponsor: Vanderbilt University • Aim: Prevention
Last updated Jun 23, 2026 11:59 UTC
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New program boosts language skills in Spanish-Speaking toddlers
Symptom relief CompletedThis study tested a program called EMT en Español that helps Spanish-speaking toddlers with language delays improve their communication and school readiness. 81 families with children aged 30-36 months took part. The program involved both therapists and caregivers working togethe…
Phase: NA • Sponsor: Vanderbilt University • Aim: Symptom relief
Last updated Jun 22, 2026 12:09 UTC
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Cutting pills, boosting lives: new approach helps dementia patients ditch unnecessary meds
Symptom relief CompletedThis pilot study tested a program called Shed-MEDS in 18 assisted living residents with dementia. The goal was to safely reduce or stop unnecessary or harmful medications based on medical guidelines and personal preferences. Researchers tracked how many medications were reduced o…
Phase: NA • Sponsor: Vanderbilt University • Aim: Symptom relief
Last updated Jun 18, 2026 11:49 UTC
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Robot companions fight apathy in Alzheimer's patients
Symptom relief CompletedThis study tested whether a socially assistive robot could reduce apathy in older adults with mild cognitive impairment or Alzheimer's disease living in long-term care. 142 participants were randomly assigned to either usual activities or usual activities plus robot-led sessions.…
Phase: PHASE1, PHASE2 • Sponsor: Vanderbilt University • Aim: Symptom relief
Last updated Jun 17, 2026 12:05 UTC
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Virtual hugs: AR headsets battle senior loneliness
Symptom relief CompletedThis study tested whether using augmented reality (AR) headsets could help older adults feel less lonely. Sixteen older adults and their family members used AR to do activities together over 4 weeks. Researchers measured how easy and enjoyable the technology was to use, and wheth…
Phase: NA • Sponsor: Vanderbilt University • Aim: Symptom relief
Last updated Jun 16, 2026 12:54 UTC
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ACL surgery patients studied for arthritis risk factors
Knowledge-focused CompletedThis study followed 432 people who had ACL reconstruction surgery to see who develops osteoarthritis years later. Researchers measured knee joint space on x-rays and looked at injury details, surgical factors, and patient traits. The goal is to identify risk factors that could he…
Sponsor: Vanderbilt University • Aim: Knowledge-focused
Last updated Jun 23, 2026 20:49 UTC
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New approach helps vulnerable residents plan future healthcare
Knowledge-focused CompletedThis pilot study tested a trauma-informed advance care planning (ACP) intervention for 30 adults living in affordable housing in Nashville. The program involved a single, flexible conversation guided by a checklist adapted from existing ACP guides. Researchers measured changes in…
Phase: NA • Sponsor: Vanderbilt University • Aim: Knowledge-focused
Last updated Jun 23, 2026 11:55 UTC
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Tutoring boost for struggling First-Graders: study tests what works
Knowledge-focused CompletedThis study looked at whether extra help in reading and math can improve skills for first-graders who start school behind in these areas. 385 students were randomly assigned to receive reading tutoring, math tutoring, both, or their school's usual program for 15 weeks. Researchers…
Phase: NA • Sponsor: Vanderbilt University • Aim: Knowledge-focused
Last updated Jun 18, 2026 11:48 UTC
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8,000 volunteers help uncover colon polyp risks
Knowledge-focused CompletedThis study looked at why some people develop colorectal polyps (growths that can turn into cancer) and others do not. Researchers collected blood, urine, saliva, and tissue samples from over 8,000 adults getting a colonoscopy. They also gathered information about lifestyle and he…
Sponsor: Vanderbilt University • Aim: Knowledge-focused
Last updated Jun 17, 2026 12:05 UTC
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New program helps families of kids with autism get the services they need
Knowledge-focused CompletedThis study tested a family navigator program and a smartphone app to help low-resourced families of young children (ages 3-5) with autism find and access services. 52 families took part. The program aimed to improve parents' knowledge, skills, and confidence in getting support fo…
Phase: NA • Sponsor: Vanderbilt University • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:07 UTC
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Flu shot mystery: why some seniors keep antibodies longer
Knowledge-focused CompletedThis study looked at why some older adults (age 50 and up) maintain flu-fighting antibodies longer after getting the flu vaccine. Researchers enrolled 510 people and measured their immune response over time. The goal was to understand factors that help maintain protection, not to…
Sponsor: Vanderbilt University • Aim: Knowledge-focused
Last updated Jun 12, 2026 12:05 UTC