Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Teaching joy: new program targets anhedonia in kids of depressed moms

NCT ID NCT05988138

Prevention Sponsor: Vanderbilt University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jul 10, 2026 · Updated 2 times

Summary

This study tested whether an 8-week program focused on boosting positive emotions could improve how children of mothers with depression process rewards. 73 children aged 8-12 and their mothers participated. The program used cognitive and behavioral skills to up-regulate positive emotions, and the researchers measured brain responses to rewards using EEG.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Family Promoting Positive Emotions (behavioral intervention)
What this could lead to
If successful, this could point toward a prevention strategy for anhedonia and depression in at-risk youth.
What could go wrong
This is a small, early-stage study with 73 participants, focused on brain activity measures rather than clinical outcomes. Results may not generalize or lead to a proven prevention method.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

73 people

The number who actually took part.

Started

Nov 2023

Finished

Jan 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

8 to 12 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Biological mothers with past or current MDD with anhedonia and their 8- to 12-year-old children * Child and biological mother can read and speak fluently in English * Child and mother have access to a computer or tablet and internet for videoconferencing * For compensation purposes, child and biological mothers must be U.S. citizens Exclusion Criteria: * Children with past or current major depressive disorder (MDD) and/or anhedonia lasting most of the day, nearly every day for at least 2 weeks based on semi-structured interviews will be excluded * Mothers or children with intellectual or developmental disabilities * Mothers with past 6 months substance use disorder with moderate or greater severity * Children or mothers with a lifetime history of a manic or hypomanic episode/bipolar disorder * Children or mothers with a psychotic disorder (e.g., schizophrenia) * Children or mothers with visual or hearing impairments that interfere with completing study measures and sessions * Child offspring of a mother who has previously participated in the study with another biological child * Children taking medications for emotional or behavioral problems other than SSRIs (stable dose for 6 weeks before time of enrollment) or psychostimulants

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Anhedonia are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

Anhedonia Depression depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anhedonia Depression

Contacts and locations

Locations

  • Jesup/Hobbs Building

    Nashville, Tennessee, 37203, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.