University Of Zurich

This study tests a new therapy for preterm babies born before 32 weeks who show abnormal general movements, a sign of possible developmental problems like cerebral palsy. The therapy involves gently guiding the baby's stiff or cramped movements into more normal, fluid patterns. R…

This early-phase study tests a new way to give immunotherapy drugs (nivolumab and ipilimumab) for patients with lung cancer or melanoma that has spread to the lining of the brain and spinal cord (leptomeningeal metastases). The drugs are given both directly into the spinal fluid …

This study looks at nearly 1,000 people with severe aortic stenosis (a narrowed heart valve) and blocked heart arteries. It compares doing artery stenting before versus after valve replacement to see which order is safer and more effective. The goal is to reduce death, heart atta…

This study compares a new technique that combines cone-beam CT scans with a robotic bronchoscope against standard methods for taking lung tissue samples. The goal is to see if the new approach can diagnose lung cancer and other lung diseases more accurately. About 300 adults who …

This study looks at whether it is safe to remove the fallopian tubes (salpingectomy) at the same time as gallbladder removal surgery in women aged 45 and older. The goal is to prevent ovarian cancer, which often starts in the fallopian tubes. About 300 women will take part, and r…

This study tests a new 3-month counseling program for people with stable COPD. The program, led by a specialized nurse, focuses on reducing emotional distress related to the disease. Fifteen participants will receive 10 counseling sessions to see if this approach is feasible and …

This study tests whether a cream containing ruxolitinib can improve skin rashes caused by anti-PD1 cancer immunotherapy. About 22 adults with this type of rash will use the cream for 12 weeks. The goal is to see if the rash clears by at least 90%.

This study aimed to see if newer MRI techniques could better detect endometriosis, a condition where tissue similar to the uterine lining grows outside the uterus, causing pain and scarring. The plan was to compare MRI results with standard ultrasound and laparoscopy. However, th…

This study tests whether a new method of radiation therapy, which uses an MRI scan to plan treatment and a CT scan to deliver it, is feasible for treating pelvic lymph node metastases. Twenty adults with confirmed cancer spread to pelvic lymph nodes will receive stereotactic body…

This study aims to see how prostate tumors change on MRI scans shortly after a precise type of radiation therapy (SBRT). Researchers will compare these MRI changes with PSA levels in the blood. The study involves 28 men with localized prostate cancer and is designed to improve un…