University Of Zurich

This study looked at whether the drug acetazolamide (Diamox) prevents acute mountain sickness (AMS) equally well in women and men. Over 300 healthy adults traveled to high altitude and took either the drug or a placebo. The goal was to see if women, who may have higher drug level…

This study tested whether doing special breathing exercises before abdominal surgery could lower the number and severity of complications after the operation. 134 adults scheduled for major belly surgery took part. They practiced breathing with a device to strengthen their breath…

This study tested whether the drug acetazolamide can reduce the rise in lung blood pressure that happens when healthy adults travel to high altitude (3600 meters). 303 men and women took either the drug or a placebo. The goal was to see if the drug's effect differs between sexes.…

This study tested a procedure called left atrial appendage occlusion (LAAO) against standard blood-thinning medications in 81 people with atrial fibrillation who were also getting a new heart valve (TAVI). The goal was to see if LAAO could prevent strokes and bleeding better than…

This study looked at whether a special type of MRI (multiparametric MRI) can more accurately determine how far bladder cancer has spread. Knowing the exact stage helps doctors decide the best treatment, such as surgery alone or chemotherapy before surgery. The study included 186 …

This study tested whether a simple home exercise program and/or protein supplements could help prevent falls in older adults at risk of muscle loss (sarcopenia). Over 800 seniors who were already frail or had low protein intake took part. The goal was to see if these easy, low-co…

This study tested whether people with pulmonary vascular disease (problems with blood vessels in the lungs) can walk the same distance in 6 minutes without extra oxygen as they can with it. 40 adults who had low oxygen levels during exercise did two walk tests—one breathing norma…

This study tested whether walking training overground with body weight support helps people with chronic spinal cord injury walk better. Fourteen participants were randomly assigned to either overground or treadmill training for four weeks. The goal was to see if real-world walki…

This study tested whether a more intense, precisely targeted type of radiation (SBRT) works better than standard radiation for reducing pain from cancer that has spread to the spine. About 219 adults with painful spinal metastases took part. The main goal was to see if SBRT leads…

This study looked at whether people with chronic lung disease who experience drops in oxygen during exercise can walk just as far without extra oxygen as with it. Forty patients completed a 6-minute walk test twice: once breathing normal air and once with low-flow oxygen. The goa…

This study tested whether combining mild electrical brain stimulation (tRNS) with white noise can temporarily reduce tinnitus symptoms. 35 adults with chronic tinnitus received either the combined treatment or brain stimulation alone. Researchers measured changes in tinnitus loud…

This study looked at whether giving extra oxygen to people who live high in the mountains and have high altitude pulmonary hypertension (a type of high blood pressure in the lungs) helps them walk farther. Twenty-four participants completed the trial. Researchers measured how far…

This study tested Pycnogenol, a natural pine bark extract, against a placebo in 153 adults with Long COVID. The goal was to see if it improves overall health and reduces symptoms like fatigue and brain fog. Participants took the supplement for 12 weeks and reported their health s…

This study tested whether a drug called acetazolamide can improve sleep-disordered breathing in women traveling to high altitude (3600 m). 303 healthy adults participated in a randomized, placebo-controlled trial. The main goal was to see if the drug reduced drops in oxygen level…

This study tested a short, low-intensity psychological program called Problem Management Plus (PM+) for refugees and asylum seekers experiencing stress and trauma. The program was delivered by non-professionals in local communities. The goal was to see if the program was feasible…

This study looked at the DNA of 9 people with primary immune deficiencies whose genetic cause was unknown. Researchers used advanced gene sequencing to try to find new mutations that lead to these disorders. The goal was to improve understanding and diagnosis, not to test a treat…

This study looked at 24 people with high-altitude pulmonary hypertension who live above 2500 meters. Researchers measured their sleep breathing at 3200 meters and again after moving to 760 meters. The goal was to see if lower altitude improves oxygen levels and reduces breathing …

This study looked at how high altitude (3600 m) affects sleep-disordered breathing in healthy women, depending on their menstrual cycle phase. 91 women spent two nights at altitude while their oxygen levels and breathing patterns were measured. The goal was to see if the menstrua…

This study looked at whether giving extra oxygen can lower blood pressure in the lungs of people who live above 2500 meters and have high altitude pulmonary hypertension. Researchers measured heart changes with ultrasound in 48 highlanders while they breathed either oxygen or reg…

This completed study from the University of Zurich looked at walking patterns in 208 people, including those with conditions like stroke, Parkinson's, multiple sclerosis, and spinal cord injury, as well as healthy volunteers. Researchers measured how gait changes after nervous sy…

This study looked at 70 people with idiopathic normal pressure hydrocephalus (iNPH), a condition that causes walking problems, memory loss, and bladder control issues. The goal was to find better ways to predict which patients would benefit from a surgery that drains extra fluid …

This study looked at how men and women's brains and hearts react to mental stress. Researchers used special brain and heart scans on 64 healthy adults aged 50-75. The goal was to understand if stress affects heart health differently based on sex. No treatment was given; this was …

This study tested a new way to measure pain in preterm infants during a procedure called LISA, where surfactant is given to help them breathe. Researchers used skin conductance, which tracks nerve signals, and compared it to a standard pain scale. The goal was to see if this meth…

This study looked at how the X10D shoe sole affects walking in 15 healthy adults aged 50 to 65. Participants walked with the X10D sole, a neutral sole, and their own sports shoes. The goal was to measure changes in foot movement and walking patterns over 3-4 weeks. It is an early…

This study looked at whether using a gentle breathing support (noninvasive ventilation) during the placement of a breathing tube in newborns can make the procedure safer and more successful. Researchers observed 50 infants who needed a breathing tube in the delivery room or inten…

This study looked at how a robotic body-weight support system called 'the FLOAT' changes the way people with incomplete spinal cord injury perform everyday tasks like walking, standing up, and climbing stairs. About 65 participants (both healthy volunteers and those with spinal i…

This study looked at 24 people with high altitude pulmonary hypertension (HAPH) who live above 2,500 meters. Researchers measured their lung blood pressure at 3,200 meters and then after moving to 760 meters for one night and seven nights. The goal was to see if simply being at a…

This study looked at whether chemicals in saliva can show when a driver is dangerously sleepy. Over 500 drivers stopped by police in Belgium gave a saliva sample and reported their sleepiness level. Researchers hope to find a biological marker that could one day be used to preven…

This study checked if adults with house dust mite allergy and seafood allergy are also sensitive to edible insects. 96 people took part. Researchers used skin tests and blood tests to see patterns. The goal was to understand who might be at risk for insect food allergies.

This study looked at 24 people with high altitude pulmonary hypertension who live above 8,200 feet. Researchers measured how far they could walk in 6 minutes at their home altitude (10,500 feet) and after moving to a lower altitude (2,500 feet). The goal was to see if relocating …

This study tested whether drugs that boost serotonin (like some psychedelics) increase pro-social behavior compared to drugs that boost dopamine. 122 healthy adults completed tasks measuring empathy, generosity, and social bonding. The goal was to understand how brain chemicals i…

This study tested whether a special type of MRI (multiparametric MRI) can reliably measure kidney function in people with metabolic syndrome—a cluster of conditions like obesity, high blood pressure, and high blood sugar. Researchers compared MRI results between 46 healthy volunt…

This study looked at how lung volume changes when stable preterm babies are placed in car seats. Using a special imaging technique, researchers measured breathing in 51 infants born before 37 weeks. The goal was to understand if the semi-upright car seat position affects lung aer…

This completed study looked at nearly 500 adults with irritable bowel syndrome (IBS) to see how common FODMAP intolerance and joint hypermobility are. Researchers tested participants with breath tests and physical exams, and explored how these factors relate to gut bacteria and b…

This study looked at 366 people who had a type of bleeding stroke called aneurysmal subarachnoid hemorrhage. Researchers measured hemoglobin levels in their spinal fluid to see if it could predict secondary brain injury, such as delayed brain damage or artery narrowing. The goal …

This study tested whether personalized walking training based on detailed 3D movement analysis works better than standard walking therapy. 63 people with spinal cord damage from injury or multiple sclerosis took part. The goal was to see if customizing exercises to each person's …

This study followed 91 healthy women traveling to 3600 meters altitude to see if their menstrual cycle phase influenced their risk of acute mountain sickness (AMS). Researchers tracked symptoms like headache and nausea using standard questionnaires. The goal was to understand whe…

This study tested whether digital intraoral scans are as accurate as traditional dental impressions for capturing full-arch teeth. Ten healthy adults received both conventional impressions and multiple digital scans. Researchers compared the scans to see how precise and true the …

This study looked at whether the BCG vaccine, normally used to prevent tuberculosis, could reduce the amount of hidden HIV in the body (the latent reservoir) in people already on HIV medication. Sixty adults with well-controlled HIV took part. The main goal was to measure changes…