Your walk could diagnose brain disease
NCT ID NCT02165787
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study from the University of Zurich looked at how people with different neurological conditions walk. Researchers measured walking patterns in 208 adults, including those with stroke, Parkinson's, multiple sclerosis, and spinal cord injury, as well as healthy volunteers. The goal was to create detailed 'gait profiles' that could help doctors better understand and diagnose brain and nerve disorders based on how a person moves.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors better understand and diagnose neurological diseases by analyzing how people walk.
- What could go wrong
- This is an observational study, not a treatment trial. It aims to gather data, not test a therapy, so it won't directly improve patient outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
208 people
The number who actually took part.
- Start date
-
Apr 2014
- Finished
-
Dec 2019
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult patients aged 18-80 with spinal cord injury, hemispheric stroke, multiple sclerosis, Parkinson disease, vestibular disease, cerebellar disease. Healthy control subjects aged 18-80.
- Ages
-
18 to 80 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Patients: * age 18 - 80 * written, informed consent * one of the following established diagnoses: unilateral stroke affecting motor system, Parkinson syndrome, cerebellar disease, vestibular dysfunction, spinal cord injury, multiple sclerosis * Brain and whole spine T1, T2 \& FLAIR magnetic resonance imaging performed within the last four months and available for study purposes or no contraindications to performing these scans Healthy subjects: * age 18 - 80 * written informed consent Exclusion Criteria: Patients: * Colour-blindness * Known to be pregnant or breastfeeding * Body mass index (weight in kg/height in metres squared) \>40 Unable to walk 50m within 6 minutes (with or without walking aids) Inability to undertake any component of the trial protocol * Terminal diagnosis with life expectancy less than six months * Cognitive disturbance defined as MMSE \< 25 Clinically significant comorbidities such as severe cardiovascular, pulmonary or malignant disease Healthy subjects: * Colour-blindness * Known to be pregnant or breastfeeding * Body mass index (weight in kg/height in metres squared) \>40 Unable to walk 50m within 6 minutes * Reliance on walking aids / prostheses for mobilisation * Significant neurological or orthopaedic diagnosis with potential impact on gait // Previous operations on the lower limbs or spine with potential impact on gait Inability to undertake any component of the trial protocol Clinically significant conditions such as severe cardiovascular, pulmonary or malignant disease
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Cerebellar disease are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Zurich
Zurich, Canton of Zurich, 8008, Switzerland
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can exercise rebuild muscle and balance in MS?
- Can a Self-Balancing exoskeleton make daily tasks more satisfying than a wheelchair?
- Can diet ease the crushing fatigue of multiple sclerosis?
- One-Time CAR-T infusion tested against progressive MS
- Can PET scans reveal hidden brain inflammation in MS?
- Can a pill rebuild the Brain's insulation? MS trial puts remyelination to the test