University Of Zurich

This study tests a method called pharmacoscopy, where a patient's tumor tissue is analyzed in the lab to find which drugs might work best for them. The goal is to see if this personalized approach is feasible for people with brain tumors that have not responded to standard treatm…

This pilot study tests whether transferring gut bacteria from a healthy donor (fecal microbiota transplant) can change the gut microbiome of 30 people with type 2 diabetes and stable coronary artery disease. Participants receive the transplant via colonoscopy and are monitored fo…

This study tests a weekly, image-guided radiation therapy (SBRT) for men with very high-risk prostate cancer that may have spread to nearby lymph nodes. The treatment uses weekly CT or MRI scans to adapt the radiation dose precisely to the tumor. The main goals are to see if this…

This phase II trial tests whether vortioxetine, a drug currently used for depression, can help people with newly diagnosed glioblastoma. The study will enroll 78 adults and measure if the drug extends the time before the cancer worsens. Vortioxetine was selected because lab tests…

This study tests whether a new MRI contrast agent, gadopiclenol, can detect brain metastases earlier than standard methods in 180 patients with advanced lung, breast, or skin cancer. Participants will receive screening brain MRIs to compare diagnosis timing and accuracy. The goal…

This study tests if a new flexible cable (SuperCable) is better than standard steel wire for closing the breastbone after heart surgery. About 86 adults will be randomly assigned to one method. The goal is to see if SuperCable leads to faster bone healing, less pain, and shorter …

This study looks at whether a special low-field MRI scanner can give clearer images for prostate cancer radiation therapy in people who have both hips replaced. Standard MRI often creates blurry images around metal implants, making it hard to aim the radiation precisely. The rese…

This study looks at whether breathing extra oxygen can improve mental performance in healthy people who live at around 2500 meters elevation. Fifty Kyrgyz adults will receive either real oxygen or a sham treatment through a nasal tube, then take tests of reaction time, attention,…

This study aims to better understand heart failure by combining detailed patient information with advanced molecular analysis. Researchers will study blood samples from 500 adults with heart failure to find specific molecules, called non-coding RNAs, that may be linked to the dis…

This study looks at how well the body handles phosphate from food as people age and whether men and women respond differently. Researchers will give a phosphate drink to 40 healthy volunteers (young adults aged 18-25 and older adults aged 63-70) and measure phosphate levels in th…

This study looks at a new way to assess pain in intensive care patients who are on breathing machines and cannot speak. It uses a special tool (AlgiScan) and a behavioral checklist to adjust pain medicine more safely. Researchers will compare data from 400 adults to see if the ne…

This study will ask 1800 young people and people with low incomes in Lucerne and Zurich how satisfied they are with free HIV and STI testing and counseling. The goal is to see if these free services work well and are easy to access. Participants just fill out a questionnaire afte…

This study looks at how different ways of processing soy (like heating or fermenting) change its ability to cause allergic reactions. Researchers will test processed soy in the lab and then on the skin of 55 adults with soy allergy. The goal is to understand which processing meth…