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Oxygen on the go: do patients really need it during exercise?

NCT ID NCT06384534

First seen Jan 04, 2026 · Last updated Jun 23, 2026 · Updated 30 times

Summary

This study tested whether people with pulmonary vascular disease (problems with blood vessels in the lungs) can walk the same distance in 6 minutes without extra oxygen as they can with it. 40 adults who had low oxygen levels during exercise did two walk tests—one breathing normal air and one breathing extra oxygen through a nasal tube. The goal was to see if skipping oxygen makes a meaningful difference in how far they can walk.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University Hospital Zürich

    Zurich, Canton of Zurich, 8091, Switzerland

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

supplemental oxygen therapy (nasal low oxygen)

What this could lead to

If it works, this could show that some patients don't need portable oxygen during exercise, simplifying daily life.

What could go wrong

This is a small, completed study with only 40 participants, so results may not apply to everyone. It only looked at short-term walking distance, not long-term benefits or risks.

Conditions

The condition(s) this trial relates to.

chronic thromboembolic pulmonary hypertension pulmonary arterial hypertension pulmonary hypertension

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.