New hope for patients with rare brain lining cancer spread
NCT ID NCT05598853
First seen Nov 01, 2025 · Last updated Jun 15, 2026 · Updated 27 times
Summary
This early-phase study tests a new way to give immunotherapy drugs (nivolumab and ipilimumab) for patients with lung cancer or melanoma that has spread to the lining of the brain and spinal cord (leptomeningeal metastases). The drugs are given both directly into the spinal fluid and through a vein. The goal is to find the safest dose and see if this approach can control the disease. The study involves 26 participants and is currently active but not recruiting.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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University Hospital Basel
Basel, Switzerland
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University Hospital Geneva
Geneva, Switzerland
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University Hospital Zurich
Zurich, Canton of Zurich, Switzerland
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.