University Of South Carolina

This study aims to find the best way to help people living in rural areas lose weight using a digital program. Over 600 adults with overweight or obesity will test different combinations of human support, such as group video chats, personal coaching calls, and feedback on their p…

This study tests a cloud-connected blood pressure monitoring program for new mothers with high blood pressure disorders. The goal is to see if remote monitoring helps more women track their blood pressure after giving birth and reduces hospital readmissions. About 540 pregnant an…

This study looks at whether adding a community health worker-led lifestyle program to remote blood pressure monitoring helps women who had high blood pressure during pregnancy better control their blood pressure and improve heart health after giving birth. About 240 women will ta…

This study tests whether a 6-month diet change can reduce inflammation and improve metabolism in obese adults who have had colon polyps. Participants and their household partners will follow a special eating plan. The goal is to see if diet can lower the risk of developing colore…

This study explores whether mindful walking—combining walking with simple mindfulness techniques—can improve brain function in older adults at risk for Alzheimer's and related dementias. Researchers will enroll 54 sedentary adults aged 60 and older with risk factors like family h…

This study looks at whether offering free center-based childcare during the summer can help prevent unhealthy weight gain in preschoolers from low-income households. Researchers will enroll 300 children who attend needs-based pre-K programs. The goal is to see if the structure an…

This study tests a supervised exercise and coaching program for adults with mild-moderate cognitive impairment. Participants will exercise twice a week at moderate intensity, including cardio, strength, and balance training. The goal is to see if the program is practical and enjo…

This study tests whether speech therapy delivered remotely (via computer) works as well as in-person therapy for people with aphasia, a language disorder caused by stroke. Researchers will enroll 100 adults who had a stroke at least a year ago and compare improvements in speech a…

This study tests whether a non-invasive brain stimulation technique called rTMS can improve word-finding in people who have trouble speaking after a stroke. Researchers will use MRI scans to guide the stimulation and see how the brain responds. The trial involves 45 participants …

This study looks at which extra features added to an online exercise program help people who have had a knee replacement become more active. About 336 adults who had knee surgery at least a year ago and currently do little exercise will take part. Researchers will track changes i…

This study looks at how three different levels of physical activity—45, 90, or 150 minutes per week—affect arthritis symptoms like pain and mobility. Researchers will enroll 285 adults with arthritis, rheumatoid arthritis, gout, fibromyalgia, osteoarthritis, or lupus. Participant…

This study looks at whether snacking on pistachios for four days can improve how the body uses energy (metabolic flexibility) in healthy overweight and obese adults aged 25-45. Participants will compare pistachio snacking to their normal diet, with measurements taken at rest, dur…

This study follows 50 adults who are about to start GLP-1 therapy for obesity or type 2 diabetes. Researchers will track how their eating habits change over 12 weeks using diet quality scores and body weight. The goal is to understand what dietary support people need while on the…

This study looks at whether a digital program that teaches teams how to support each other can help inactive adults become more physically active. About 300 adults who are not meeting exercise guidelines will join with friends or family in teams of 3-8. The program uses online to…

This study tests a smartphone app designed to help adults taking GLP-1 medications for obesity or type 2 diabetes eat better. About 50 participants will use the app for 6 weeks to track their diet and learn about nutrition. The goal is to see if the app is helpful and easy to use…