University Of Michigan Rogel Cancer Center

This study tested whether a dietary supplement made from potato starch could reduce the risk of graft-versus-host disease (GVHD) in people receiving a stem cell transplant. GVHD is a serious condition where the donor cells attack the patient's body. The supplement was given to 10…

This study tested a combination of two drugs, nivolumab and cabiralizumab, in 4 adults with a rare and aggressive blood cancer called peripheral T-cell lymphoma that had come back or not responded to prior treatments. The goal was to see if the combination could shrink tumors. Th…

This study tested a new way to give radiation therapy to people with advanced head and neck cancer. Doctors used a special MRI scan to find parts of the tumor that are most resistant to standard radiation and gave those areas a higher dose, while keeping normal doses to healthy t…

This study tested whether metformin, a common diabetes drug, could help control chronic lymphocytic leukemia (CLL) in 37 patients whose cancer had returned or who had a high-risk genetic type. Metformin is cheap and generally safe, and it may slow cancer growth by lowering insuli…

This study tested a combination of the immunotherapy drug nivolumab with three chemotherapy drugs (nanoliposomal-irinotecan, 5-fluorouracil, and leucovorin) in 34 people with advanced biliary tract cancer that had worsened after initial treatment. The goal was to see if the combo…

This study looked at men with a type of advanced prostate cancer that no longer responds to hormone therapy and has only a few spots of spread (oligometastatic). It tested whether adding focused radiation to standard treatment could delay the cancer from getting worse. The trial …

This study tested whether adding the immunotherapy drug nivolumab to standard radiation and chemotherapy could help people with high-risk HPV-related throat cancer live longer without their cancer growing. Twenty-six participants received the combination treatment. The goal was t…

This study looked at whether taking omeprazole (a heartburn drug) and low-dose aspirin daily for about a month can help prevent colon polyps in people at high risk. 21 adults with a history of many polyps took both pills before their first meal each day. Researchers took small ti…

This study tested a surgical procedure called RPNI to treat chronic pain that can occur after mastectomy (breast removal). The goal was to reduce pain, decrease the need for opioid painkillers, and improve quality of life. 26 participants were followed for about a year to measure…

This study looked at whether self-acupressure—applying gentle pressure to specific points on the body—can reduce joint pain and stiffness caused by aromatase inhibitor therapy in postmenopausal women with breast cancer. Fifty participants learned to do acupressure at home and rep…

This study looked at whether acupressure, a technique where you apply gentle pressure to specific points on the body, can help reduce severe tiredness (fatigue) in women who have had ovarian cancer. 171 survivors who had finished their main cancer treatments (like surgery and che…

This study tested whether young cancer survivors (ages 15-39) could learn to press on specific body spots (acupressure) to help with tiredness. 42 people who had finished cancer treatment at least 3 months ago and still felt very tired took part. They were taught how to do acupre…

This study tested whether a simple at-home writing program could help teens and young adults who have finished cancer treatment feel less distressed about their body image and reduce anxiety. Thirty survivors aged 15-39 participated in a four-week expressive writing program. The …

This study tested whether omega-3 fatty acid supplements can reduce joint pain and stiffness caused by aromatase inhibitor therapy in postmenopausal women with hormone receptor positive breast cancer. 77 participants took omega-3 supplements soon after starting their cancer medic…

This study looked at whether a mobile phone app called Roadmap 2.0 could improve the quality of life for caregivers and patients going through a stem cell transplant. 372 caregivers and patients took part. The app was designed to provide support and track health, with the goal of…

This study tested a new tool called CQUPLE to see if it helps patients with low-risk thyroid cancer make better-informed treatment decisions. Fifty adults aged 18 to 80 with newly diagnosed low-risk thyroid cancer took part. Half received the CQUPLE tool before their surgeon visi…

This study looked at whether a new type of CT scan (dual-energy CT) can take better pictures of tumors during radiation therapy for pelvic and urinary cancers. 30 adults who were already getting standard radiation treatment had extra scans with the new method. The goal was to com…

This study looked at whether a special website or two phone calls with a health coach could encourage more people with a personal or family history of certain cancers to get genetic testing. Over 800 adults who already completed a family health survey were randomly assigned to on…

This pilot study tested a web-based tool called MAP to help men aged 55+ with low-risk prostate cancer stay on active surveillance. The tool provides information and reminders about needed tests and how their primary care doctor can help. The study enrolled 39 men and measured ho…

This study looked at whether a virtual platform can help cancer patients share genetic testing information with their relatives. Over 3,000 cancer patients with certain gene changes took part. The goal was to see if more family members would get tested for cancer risk, helping th…