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Heartburn drug and aspirin combo may stop colon polyps

NCT ID NCT06378398

First seen Feb 01, 2026 · Last updated May 23, 2026 · Updated 12 times

Summary

This study looked at whether taking omeprazole (a heartburn drug) and low-dose aspirin daily for about a month can help prevent colon polyps in people at high risk. 21 adults with a history of many polyps took both pills before their first meal each day. Researchers took small tissue samples before and after treatment to check for changes linked to cancer prevention.

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Contacts and locations

Locations

  • Ohio State University Comprehensive Cancer Center

    Columbus, Ohio, 43210, United States

  • The University of Michigan Rogel Cancer Center

    Ann Arbor, Michigan, 48109, United States

Conditions

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