University Of Michigan Rogel Cancer Center

This study is testing whether a combination of two drugs, olaparib and AZD6738, can help control advanced prostate cancer that has spread and no longer responds to standard hormone treatments. It will involve about 49 men to see how well the drugs work together and how safe they …

This study is testing whether a combination of targeted radiation and a specific set of drugs can better control prostate cancer that has spread to only a few other places in the body. It involves 21 men who have already had initial treatment for their prostate cancer. The goal i…

This study is testing a new oral drug called APG-115 for people with a specific type of advanced salivary gland cancer. The main goals are to find a safe and effective dose and to see if the drug can shrink tumors. It involves 41 participants whose cancer has a normal p53 gene an…

This study is testing whether a combination of two drugs, pembrolizumab and lenvatinib, can help control an aggressive form of prostate cancer that has spread. It is for men whose cancer has developed neuroendocrine features and has stopped responding to standard hormone therapie…

This study is testing whether adding a drug called venetoclax to a standard chemotherapy regimen (FLAG or CLAG) is more effective for treating newly diagnosed secondary acute myeloid leukemia (sAML). The main goal is to see if this combination helps more patients achieve complete…

This study is testing a new, more precise way to deliver radiation therapy to people newly diagnosed with glioblastoma, a fast-growing brain tumor. Doctors will use advanced MRI scans during treatment to target higher radiation doses specifically to the most resistant parts of th…

This study is testing if adding a drug called vorinostat to standard medications can better prevent graft-versus-host disease (GVHD) in children and young adults getting a bone marrow transplant for blood cancers. GVHD is a serious complication where the donor's immune cells atta…

This study is testing whether a virtual, 8-week music relaxation program can help reduce anxiety in teens and young adults who have finished cancer treatment. Researchers are enrolling 50 participants aged 15-39 who report significant anxiety. The main goal is to see if this type…

This study is gathering information to see if certain postmenopausal women with early-stage, hormone-sensitive breast cancer might safely avoid radiation treatment after lumpectomy surgery. The women in this study have a specific low-risk tumor profile and will take hormone-block…