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Diabetes drug metformin shows promise in slowing CLL progression

NCT ID NCT01750567

First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 24 times

Summary

This study tested whether metformin, a common diabetes drug, could help control chronic lymphocytic leukemia (CLL) in 37 patients whose cancer had returned or who had a high-risk genetic type. Metformin is cheap and generally safe, and it may slow cancer growth by lowering insulin levels and blocking certain cell signals. The goal was to see if metformin could delay the need for stronger treatments.

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Contacts and locations

Locations

  • University of Michigan Comprehensive Cancer Center

    Ann Arbor, Michigan, 48109, United States

Conditions

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